Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PDK4> ?p ?o. }
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- PDK4 abstract "Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. It codes for an isozyme of pyruvate dehydrogenase kinase.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, reducing the conversion of pyruvate, which is produced from the oxidation of glucose and amino acids, to acetyl-CoA and contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. PDK4 is increased in hibernation and helps to decrease metabolism and conserve glucose by decreasing its conversion to acetyl-CoA, which enters the citric acid cycle and is converted to ATP.".
- PDK4 entrezgene "5166".
- PDK4 wikiPageID "14758053".
- PDK4 wikiPageRevisionID "592758960".
- PDK4 hasPhotoCollection PDK4.
- PDK4 requireManualInspection "no".
- PDK4 updateCitations "yes".
- PDK4 updatePage "yes".
- PDK4 updateProteinBox "yes".
- PDK4 updateSummary "yes".
- PDK4 type Biomolecule.
- PDK4 type Protein.
- PDK4 type BiologicalObject.
- PDK4 comment "Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. It codes for an isozyme of pyruvate dehydrogenase kinase.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain.".
- PDK4 label "PDK4".
- PDK4 sameAs m.03gwy8l.
- PDK4 sameAs Q7118827.
- PDK4 sameAs Q7118827.
- PDK4 wasDerivedFrom PDK4?oldid=592758960.
- PDK4 isPrimaryTopicOf PDK4.