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- PFKFB2 abstract "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 is an enzyme that in humans is encoded by the PFKFB2 gene.The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.".
- PFKFB2 entrezgene "5208".
- PFKFB2 wikiPageID "14818366".
- PFKFB2 wikiPageRevisionID "592772128".
- PFKFB2 hasPhotoCollection PFKFB2.
- PFKFB2 requireManualInspection "no".
- PFKFB2 summaryText "The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.".
- PFKFB2 updateCitations "yes".
- PFKFB2 updatePage "yes".
- PFKFB2 updateProteinBox "yes".
- PFKFB2 updateSummary "yes".
- PFKFB2 type Biomolecule.
- PFKFB2 type Protein.
- PFKFB2 type BiologicalObject.
- PFKFB2 comment "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 is an enzyme that in humans is encoded by the PFKFB2 gene.The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes.".
- PFKFB2 label "PFKFB2".
- PFKFB2 sameAs m.03gy_x7.
- PFKFB2 sameAs Q7119094.
- PFKFB2 sameAs Q7119094.
- PFKFB2 wasDerivedFrom PFKFB2?oldid=592772128.
- PFKFB2 isPrimaryTopicOf PFKFB2.