Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PIAS1> ?p ?o. }
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- PIAS1 abstract "E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.".
- PIAS1 entrezgene "8554".
- PIAS1 wikiPageID "14723758".
- PIAS1 wikiPageRevisionID "602082104".
- PIAS1 hasPhotoCollection PIAS1.
- PIAS1 requireManualInspection "no".
- PIAS1 summaryText "This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 ] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor . It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.".
- PIAS1 updateCitations "yes".
- PIAS1 updatePage "yes".
- PIAS1 updateProteinBox "yes".
- PIAS1 updateSummary "yes".
- PIAS1 type Biomolecule.
- PIAS1 type Protein.
- PIAS1 type BiologicalObject.
- PIAS1 comment "E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR).".
- PIAS1 label "PIAS1".
- PIAS1 sameAs m.03gvlkz.
- PIAS1 sameAs Q7119300.
- PIAS1 sameAs Q7119300.
- PIAS1 wasDerivedFrom PIAS1?oldid=602082104.
- PIAS1 isPrimaryTopicOf PIAS1.