Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PPM1F> ?p ?o. }
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- PPM1F abstract "Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene.The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.".
- PPM1F entrezgene "9647".
- PPM1F wikiPageID "15419843".
- PPM1F wikiPageRevisionID "592840557".
- PPM1F hasPhotoCollection PPM1F.
- PPM1F requireManualInspection "no".
- PPM1F summaryText "The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors , and thus block the effects of p21-activated kinase 1 , a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.".
- PPM1F updateCitations "yes".
- PPM1F updatePage "yes".
- PPM1F updateProteinBox "yes".
- PPM1F updateSummary "yes".
- PPM1F type Biomolecule.
- PPM1F type Protein.
- PPM1F type BiologicalObject.
- PPM1F comment "Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene.The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases.".
- PPM1F label "PPM1F".
- PPM1F sameAs m.03m81w4.
- PPM1F sameAs Q7120129.
- PPM1F sameAs Q7120129.
- PPM1F wasDerivedFrom PPM1F?oldid=592840557.
- PPM1F isPrimaryTopicOf PPM1F.