Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PPOX> ?p ?o. }
Showing items 1 to 34 of
34
with 100 items per page.
- PPOX abstract "Protoporphyrinogen oxidase is an enzyme that in humans is encoded by the PPOX gene.This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. This protein is a flavoprotein associated with the outer surface of the inner mitochondrial membrane. Mutations in this gene cause variegate porphyria.PPOX (protoporphyrinogen oxidase) is a human gene that produces an enzyme called protoporphyrinogen oxidase. This enzyme is responsible for the seventh step in heme production. Heme is the portion of hemoglobin that carries oxygen in the blood from the lungs to the rest of the body. Each of the steps in heme production is controlled by a separate gene (see below). Protoporphyrinogen oxidase removes hydrogen atoms from protoporphyrinogen IX (the product of the sixth step in the production of heme) to form protoporphyrin IX. One additional enzyme must modify protoporphyrin IX before it becomes heme.The PPOX gene is located on the long (q) arm of chromosome 1 at position 22, from base pair 157,949,266 to base pair 157,954,082.The following genes are part of the chemical pathway for making heme. ALAD: aminolevulinate, delta-, dehydratase ALAS1: aminolevulinate, delta-, synthase 1 ALAS2: aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) CPOX: coproporphyrinogen oxidase FECH: ferrochelatase (protoporphyria) HMBS: hydroxymethylbilane synthase PPOX: protoporphyrinogen oxidase UROD: uroporphyrinogen decarboxylase UROS: uroporphyrinogen III synthase (congenital erythropoietic porphyria)↑ ↑ ↑ 3.0 3.1".
- PPOX entrezgene "5498".
- PPOX wikiPageExternalLink ghr.nlm.nih.gov.
- PPOX wikiPageID "3599573".
- PPOX wikiPageRevisionID "592840617".
- PPOX hasPhotoCollection PPOX.
- PPOX requireManualInspection "no".
- PPOX summaryText "This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. This protein is a flavoprotein associated with the outer surface of the inner mitochondrial membrane. Mutations in this gene cause variegate porphyria.".
- PPOX updateCitations "yes".
- PPOX updatePage "yes".
- PPOX updateProteinBox "yes".
- PPOX updateSummary "yes".
- PPOX subject Category:Human_genes.
- PPOX type Abstraction100002137.
- PPOX type Arrangement107938773.
- PPOX type Gene105436752.
- PPOX type Genes.
- PPOX type Group100031264.
- PPOX type Ordering108456993.
- PPOX type Sequence108459252.
- PPOX type Series108457976.
- PPOX type Biomolecule.
- PPOX type Protein.
- PPOX type BiologicalObject.
- PPOX comment "Protoporphyrinogen oxidase is an enzyme that in humans is encoded by the PPOX gene.This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. This protein is a flavoprotein associated with the outer surface of the inner mitochondrial membrane. Mutations in this gene cause variegate porphyria.PPOX (protoporphyrinogen oxidase) is a human gene that produces an enzyme called protoporphyrinogen oxidase.".
- PPOX label "PPOX".
- PPOX sameAs PPOX.
- PPOX sameAs m.09p1_4.
- PPOX sameAs Q7120137.
- PPOX sameAs Q7120137.
- PPOX sameAs PPOX.
- PPOX sameAs PPOX.
- PPOX wasDerivedFrom PPOX?oldid=592840617.
- PPOX isPrimaryTopicOf PPOX.