Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PPP3CC> ?p ?o. }
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- PPP3CC abstract "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PPP3CC gene.Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]".
- PPP3CC entrezgene "5533".
- PPP3CC wikiPageID "15351014".
- PPP3CC wikiPageRevisionID "592841353".
- PPP3CC hasPhotoCollection PPP3CC.
- PPP3CC requireManualInspection "no".
- PPP3CC summaryText "Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha , calcineurin A-beta , and calcineurin A-gamma , have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species .[supplied by OMIM]".
- PPP3CC updateCitations "yes".
- PPP3CC updatePage "yes".
- PPP3CC updateProteinBox "yes".
- PPP3CC updateSummary "yes".
- PPP3CC type Biomolecule.
- PPP3CC type Protein.
- PPP3CC type BiologicalObject.
- PPP3CC comment "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PPP3CC gene.Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum.".
- PPP3CC label "PPP3CC".
- PPP3CC sameAs m.03m5x0f.
- PPP3CC sameAs Q7120181.
- PPP3CC sameAs Q7120181.
- PPP3CC wasDerivedFrom PPP3CC?oldid=592841353.
- PPP3CC isPrimaryTopicOf PPP3CC.