Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PRCP> ?p ?o. }
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- PRCP abstract "Lysosomal Pro-X carboxypeptidase is an enzyme that in humans is encoded by the PRCP gene.The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.".
- PRCP entrezgene "5547".
- PRCP wikiPageID "15063544".
- PRCP wikiPageRevisionID "606062827".
- PRCP hasPhotoCollection PRCP.
- PRCP requireManualInspection "no".
- PRCP summaryText "The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.".
- PRCP updateCitations "yes".
- PRCP updatePage "yes".
- PRCP updateProteinBox "yes".
- PRCP updateSummary "yes".
- PRCP type Biomolecule.
- PRCP type Protein.
- PRCP type BiologicalObject.
- PRCP comment "Lysosomal Pro-X carboxypeptidase is an enzyme that in humans is encoded by the PRCP gene.The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein.".
- PRCP label "PRCP".
- PRCP sameAs m.03hg7v6.
- PRCP sameAs Q7120268.
- PRCP sameAs Q7120268.
- PRCP wasDerivedFrom PRCP?oldid=606062827.
- PRCP isPrimaryTopicOf PRCP.