Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PRDX3> ?p ?o. }
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- PRDX3 abstract "Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene.This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.".
- PRDX3 entrezgene "10935".
- PRDX3 wikiPageID "14770537".
- PRDX3 wikiPageRevisionID "603768676".
- PRDX3 hasPhotoCollection PRDX3.
- PRDX3 requireManualInspection "no".
- PRDX3 summaryText "This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.".
- PRDX3 updateCitations "yes".
- PRDX3 updatePage "yes".
- PRDX3 updateProteinBox "yes".
- PRDX3 updateSummary "yes".
- PRDX3 type Biomolecule.
- PRDX3 type Protein.
- PRDX3 type BiologicalObject.
- PRDX3 comment "Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene.This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide.".
- PRDX3 label "PRDX3".
- PRDX3 sameAs m.03gxd_6.
- PRDX3 sameAs Q7120277.
- PRDX3 sameAs Q7120277.
- PRDX3 wasDerivedFrom PRDX3?oldid=603768676.
- PRDX3 isPrimaryTopicOf PRDX3.