Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PRKAB2> ?p ?o. }
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- PRKAB2 abstract "5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene.The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles.".
- PRKAB2 entrezgene "5565".
- PRKAB2 wikiPageID "14814473".
- PRKAB2 wikiPageRevisionID "592853829".
- PRKAB2 hasPhotoCollection PRKAB2.
- PRKAB2 requireManualInspection "no".
- PRKAB2 summaryText "The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase and beta-hydroxy beta-methylglutaryl-CoA reductase , key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles.".
- PRKAB2 updateCitations "yes".
- PRKAB2 updatePage "yes".
- PRKAB2 updateProteinBox "yes".
- PRKAB2 updateSummary "yes".
- PRKAB2 type Biomolecule.
- PRKAB2 type Protein.
- PRKAB2 type BiologicalObject.
- PRKAB2 comment "5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene.The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status.".
- PRKAB2 label "PRKAB2".
- PRKAB2 sameAs m.03gyvpm.
- PRKAB2 sameAs Q7120325.
- PRKAB2 sameAs Q7120325.
- PRKAB2 sameAs 851.
- PRKAB2 wasDerivedFrom PRKAB2?oldid=592853829.
- PRKAB2 isPrimaryTopicOf PRKAB2.