Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PRKAG3> ?p ?o. }
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- PRKAG3 abstract "5'-AMP-activated protein kinase subunit gamma-3 is an enzyme that in humans is encoded by the PRKAG3 gene.The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.".
- PRKAG3 entrezgene "53632".
- PRKAG3 wikiPageID "15073314".
- PRKAG3 wikiPageRevisionID "592853958".
- PRKAG3 hasPhotoCollection PRKAG3.
- PRKAG3 requireManualInspection "no".
- PRKAG3 summaryText "The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase and beta-hydroxy beta-methylglutaryl-CoA reductase , key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.".
- PRKAG3 updateCitations "yes".
- PRKAG3 updatePage "yes".
- PRKAG3 updateProteinBox "yes".
- PRKAG3 updateSummary "yes".
- PRKAG3 type Biomolecule.
- PRKAG3 type Protein.
- PRKAG3 type BiologicalObject.
- PRKAG3 comment "5'-AMP-activated protein kinase subunit gamma-3 is an enzyme that in humans is encoded by the PRKAG3 gene.The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status.".
- PRKAG3 label "PRKAG3".
- PRKAG3 sameAs PRKAG3.
- PRKAG3 sameAs m.03hgn1_.
- PRKAG3 sameAs Q7120332.
- PRKAG3 sameAs Q7120332.
- PRKAG3 wasDerivedFrom PRKAG3?oldid=592853958.
- PRKAG3 isPrimaryTopicOf PRKAG3.