Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PRKD3> ?p ?o. }
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- PRKD3 abstract "Serine/threonine-protein kinase D3 or protein kinase C δ3 (PKC-δ3) is an enzyme that in humans is encoded by the PRKD3 gene.Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phospholipase C gamma and the involvement of other PKC family members.".
- PRKD3 entrezgene "23683".
- PRKD3 wikiPageID "14760192".
- PRKD3 wikiPageRevisionID "604398356".
- PRKD3 hasPhotoCollection PRKD3.
- PRKD3 requireManualInspection "no".
- PRKD3 summaryText "Protein kinase C is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor engagement, which requires intact phospholipase C gamma and the involvement of other PKC family members.".
- PRKD3 updateCitations "yes".
- PRKD3 updatePage "yes".
- PRKD3 updateProteinBox "yes".
- PRKD3 updateSummary "yes".
- PRKD3 type Biomolecule.
- PRKD3 type Protein.
- PRKD3 type BiologicalObject.
- PRKD3 comment "Serine/threonine-protein kinase D3 or protein kinase C δ3 (PKC-δ3) is an enzyme that in humans is encoded by the PRKD3 gene.Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.".
- PRKD3 label "PRKD3".
- PRKD3 sameAs m.03gx03x.
- PRKD3 sameAs Q7120347.
- PRKD3 sameAs Q7120347.
- PRKD3 wasDerivedFrom PRKD3?oldid=604398356.
- PRKD3 isPrimaryTopicOf PRKD3.