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- PSMB9 abstract "Proteasome subunit beta type-9 is a protein that in humans is encoded by the PSMB9 gene.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding different isoforms have been identified; both isoforms are processed to yield the same mature subunit.".
- PSMB9 entrezgene "5698".
- PSMB9 wikiPageID "14725633".
- PSMB9 wikiPageRevisionID "601783674".
- PSMB9 hasPhotoCollection PSMB9.
- PSMB9 requireManualInspection "no".
- PSMB9 summaryText "The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC . Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding different isoforms have been identified; both isoforms are processed to yield the same mature subunit.".
- PSMB9 updateCitations "yes".
- PSMB9 updatePage "yes".
- PSMB9 updateProteinBox "yes".
- PSMB9 updateSummary "yes".
- PSMB9 type Biomolecule.
- PSMB9 type Protein.
- PSMB9 type BiologicalObject.
- PSMB9 comment "Proteasome subunit beta type-9 is a protein that in humans is encoded by the PSMB9 gene.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMB9 label "PSMB9".
- PSMB9 sameAs m.03gvnyn.
- PSMB9 sameAs Q7120704.
- PSMB9 sameAs Q7120704.
- PSMB9 wasDerivedFrom PSMB9?oldid=601783674.
- PSMB9 isPrimaryTopicOf PSMB9.