Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSMC4> ?p ?o. }
Showing items 1 to 21 of
21
with 100 items per page.
- PSMC4 abstract "26S protease regulatory subunit 6B is an enzyme that in humans is encoded by the PSMC4 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.".
- PSMC4 entrezgene "5704".
- PSMC4 wikiPageID "14754060".
- PSMC4 wikiPageRevisionID "602094176".
- PSMC4 hasPhotoCollection PSMC4.
- PSMC4 requireManualInspection "no".
- PSMC4 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.".
- PSMC4 updateCitations "yes".
- PSMC4 updatePage "yes".
- PSMC4 updateProteinBox "yes".
- PSMC4 updateSummary "yes".
- PSMC4 type Biomolecule.
- PSMC4 type Protein.
- PSMC4 type BiologicalObject.
- PSMC4 comment "26S protease regulatory subunit 6B is an enzyme that in humans is encoded by the PSMC4 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMC4 label "PSMC4".
- PSMC4 sameAs m.03gwq52.
- PSMC4 sameAs Q7120709.
- PSMC4 sameAs Q7120709.
- PSMC4 wasDerivedFrom PSMC4?oldid=602094176.
- PSMC4 isPrimaryTopicOf PSMC4.