Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSMC5> ?p ?o. }
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- PSMC5 abstract "26S protease regulatory subunit 8 is an enzyme that in humans is encoded by the PSMC5 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.".
- PSMC5 entrezgene "5705".
- PSMC5 wikiPageID "14723357".
- PSMC5 wikiPageRevisionID "602094185".
- PSMC5 hasPhotoCollection PSMC5.
- PSMC5 requireManualInspection "no".
- PSMC5 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.".
- PSMC5 updateCitations "yes".
- PSMC5 updatePage "yes".
- PSMC5 updateProteinBox "yes".
- PSMC5 updateSummary "yes".
- PSMC5 type Biomolecule.
- PSMC5 type Protein.
- PSMC5 type BiologicalObject.
- PSMC5 comment "26S protease regulatory subunit 8 is an enzyme that in humans is encoded by the PSMC5 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMC5 label "PSMC5".
- PSMC5 sameAs m.03gvkv9.
- PSMC5 sameAs Q7120710.
- PSMC5 sameAs Q7120710.
- PSMC5 wasDerivedFrom PSMC5?oldid=602094185.
- PSMC5 isPrimaryTopicOf PSMC5.