Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSMC6> ?p ?o. }
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- PSMC6 abstract "26S protease regulatory subunit S10B is an enzyme that in humans is encoded by the PSMC6 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.".
- PSMC6 entrezgene "5706".
- PSMC6 wikiPageID "14754904".
- PSMC6 wikiPageRevisionID "592872127".
- PSMC6 hasPhotoCollection PSMC6.
- PSMC6 requireManualInspection "no".
- PSMC6 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.".
- PSMC6 updateCitations "yes".
- PSMC6 updatePage "yes".
- PSMC6 updateProteinBox "yes".
- PSMC6 updateSummary "yes".
- PSMC6 type Biomolecule.
- PSMC6 type Protein.
- PSMC6 type BiologicalObject.
- PSMC6 comment "26S protease regulatory subunit S10B is an enzyme that in humans is encoded by the PSMC6 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMC6 label "PSMC6".
- PSMC6 sameAs m.03gws0g.
- PSMC6 sameAs Q7120712.
- PSMC6 sameAs Q7120712.
- PSMC6 wasDerivedFrom PSMC6?oldid=592872127.
- PSMC6 isPrimaryTopicOf PSMC6.