Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSMD1> ?p ?o. }
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- PSMD1 abstract "26S proteasome non-ATPase regulatory subunit 1 is an enzyme that in humans is encoded by the PSMD1 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding.".
- PSMD1 entrezgene "5707".
- PSMD1 wikiPageID "14754916".
- PSMD1 wikiPageRevisionID "601783817".
- PSMD1 hasPhotoCollection PSMD1.
- PSMD1 requireManualInspection "no".
- PSMD1 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding.".
- PSMD1 updateCitations "yes".
- PSMD1 updatePage "yes".
- PSMD1 updateProteinBox "yes".
- PSMD1 updateSummary "yes".
- PSMD1 type Biomolecule.
- PSMD1 type Protein.
- PSMD1 type BiologicalObject.
- PSMD1 comment "26S proteasome non-ATPase regulatory subunit 1 is an enzyme that in humans is encoded by the PSMD1 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD1 label "PSMD1".
- PSMD1 sameAs m.03gws1h.
- PSMD1 sameAs Q7120711.
- PSMD1 sameAs Q7120711.
- PSMD1 sameAs 515.
- PSMD1 wasDerivedFrom PSMD1?oldid=601783817.
- PSMD1 isPrimaryTopicOf PSMD1.