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- PSMD10 abstract "26S proteasome non-ATPase regulatory subunit 10 is an enzyme that in humans is encoded by the PSMD10 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.".
- PSMD10 entrezgene "5716".
- PSMD10 wikiPageID "14156867".
- PSMD10 wikiPageRevisionID "602094192".
- PSMD10 hasPhotoCollection PSMD10.
- PSMD10 requireManualInspection "no".
- PSMD10 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.".
- PSMD10 updateCitations "yes".
- PSMD10 updatePage "yes".
- PSMD10 updateProteinBox "yes".
- PSMD10 updateSummary "yes".
- PSMD10 type Biomolecule.
- PSMD10 type Protein.
- PSMD10 type BiologicalObject.
- PSMD10 comment "26S proteasome non-ATPase regulatory subunit 10 is an enzyme that in humans is encoded by the PSMD10 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD10 label "PSMD10".
- PSMD10 label "PSMD10".
- PSMD10 sameAs PSMD10.
- PSMD10 sameAs m.03cw92p.
- PSMD10 sameAs Q7120714.
- PSMD10 sameAs Q7120714.
- PSMD10 wasDerivedFrom PSMD10?oldid=602094192.
- PSMD10 isPrimaryTopicOf PSMD10.