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- PSMD11 abstract "26S proteasome non-ATPase regulatory subunit 11 is an enzyme that in humans is encoded by the PSMD11 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.".
- PSMD11 entrezgene "5717".
- PSMD11 wikiPageID "14754931".
- PSMD11 wikiPageRevisionID "592872190".
- PSMD11 hasPhotoCollection PSMD11.
- PSMD11 requireManualInspection "no".
- PSMD11 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.".
- PSMD11 updateCitations "yes".
- PSMD11 updatePage "yes".
- PSMD11 updateProteinBox "yes".
- PSMD11 updateSummary "yes".
- PSMD11 type Biomolecule.
- PSMD11 type Protein.
- PSMD11 type BiologicalObject.
- PSMD11 comment "26S proteasome non-ATPase regulatory subunit 11 is an enzyme that in humans is encoded by the PSMD11 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD11 label "PSMD11".
- PSMD11 sameAs m.03gws25.
- PSMD11 sameAs Q7120713.
- PSMD11 sameAs Q7120713.
- PSMD11 wasDerivedFrom PSMD11?oldid=592872190.
- PSMD11 isPrimaryTopicOf PSMD11.