Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSMD2> ?p ?o. }
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- PSMD2 abstract "26S proteasome non-ATPase regulatory subunit 2 is an enzyme that in humans is encoded by the PSMD2 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.".
- PSMD2 entrezgene "5708".
- PSMD2 wikiPageID "14754922".
- PSMD2 wikiPageRevisionID "592872268".
- PSMD2 hasPhotoCollection PSMD2.
- PSMD2 requireManualInspection "no".
- PSMD2 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.".
- PSMD2 updateCitations "yes".
- PSMD2 updatePage "yes".
- PSMD2 updateProteinBox "yes".
- PSMD2 updateSummary "yes".
- PSMD2 type Biomolecule.
- PSMD2 type Protein.
- PSMD2 type BiologicalObject.
- PSMD2 comment "26S proteasome non-ATPase regulatory subunit 2 is an enzyme that in humans is encoded by the PSMD2 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD2 label "PSMD2".
- PSMD2 sameAs m.03gws1v.
- PSMD2 sameAs Q7120718.
- PSMD2 sameAs Q7120718.
- PSMD2 sameAs 522.
- PSMD2 wasDerivedFrom PSMD2?oldid=592872268.
- PSMD2 isPrimaryTopicOf PSMD2.