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- PSMD3 abstract "26S proteasome non-ATPase regulatory subunit 3 is an enzyme that in humans is encoded by the PSMD3 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.".
- PSMD3 entrezgene "5709".
- PSMD3 wikiPageID "14756803".
- PSMD3 wikiPageRevisionID "601783843".
- PSMD3 hasPhotoCollection PSMD3.
- PSMD3 requireManualInspection "no".
- PSMD3 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.".
- PSMD3 updateCitations "yes".
- PSMD3 updatePage "yes".
- PSMD3 updateProteinBox "yes".
- PSMD3 updateSummary "yes".
- PSMD3 type Biomolecule.
- PSMD3 type Protein.
- PSMD3 type BiologicalObject.
- PSMD3 comment "26S proteasome non-ATPase regulatory subunit 3 is an enzyme that in humans is encoded by the PSMD3 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD3 label "PSMD3".
- PSMD3 sameAs m.03gwwf4.
- PSMD3 sameAs Q7120719.
- PSMD3 sameAs Q7120719.
- PSMD3 wasDerivedFrom PSMD3?oldid=601783843.
- PSMD3 isPrimaryTopicOf PSMD3.