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- PSMD5 abstract "26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.".
- PSMD5 entrezgene "5711".
- PSMD5 wikiPageID "14170212".
- PSMD5 wikiPageRevisionID "592872324".
- PSMD5 hasPhotoCollection PSMD5.
- PSMD5 requireManualInspection "no".
- PSMD5 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.".
- PSMD5 updateCitations "yes".
- PSMD5 updatePage "yes".
- PSMD5 updateProteinBox "yes".
- PSMD5 updateSummary "yes".
- PSMD5 type Biomolecule.
- PSMD5 type Protein.
- PSMD5 type BiologicalObject.
- PSMD5 comment "26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD5 label "PSMD5".
- PSMD5 sameAs m.03cwr0m.
- PSMD5 sameAs Q7120721.
- PSMD5 sameAs Q7120721.
- PSMD5 wasDerivedFrom PSMD5?oldid=592872324.
- PSMD5 isPrimaryTopicOf PSMD5.