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- PSMD7 abstract "26S proteasome non-ATPase regulatory subunit 7 is an enzyme that in humans is encoded by the PSMD7 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.".
- PSMD7 entrezgene "5713".
- PSMD7 wikiPageID "14754066".
- PSMD7 wikiPageRevisionID "601783789".
- PSMD7 hasPhotoCollection PSMD7.
- PSMD7 requireManualInspection "no".
- PSMD7 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.".
- PSMD7 updateCitations "yes".
- PSMD7 updatePage "yes".
- PSMD7 updateProteinBox "yes".
- PSMD7 updateSummary "yes".
- PSMD7 type Biomolecule.
- PSMD7 type Protein.
- PSMD7 type BiologicalObject.
- PSMD7 comment "26S proteasome non-ATPase regulatory subunit 7 is an enzyme that in humans is encoded by the PSMD7 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD7 label "PSMD7".
- PSMD7 sameAs m.03gwq63.
- PSMD7 sameAs Q7120723.
- PSMD7 sameAs Q7120723.
- PSMD7 wasDerivedFrom PSMD7?oldid=601783789.
- PSMD7 isPrimaryTopicOf PSMD7.