Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSMD8> ?p ?o. }
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- PSMD8 abstract "26S proteasome non-ATPase regulatory subunit 8 is an enzyme that in humans is encoded by the PSMD8 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.".
- PSMD8 entrezgene "5714".
- PSMD8 wikiPageID "14755165".
- PSMD8 wikiPageRevisionID "592872374".
- PSMD8 hasPhotoCollection PSMD8.
- PSMD8 requireManualInspection "no".
- PSMD8 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.".
- PSMD8 updateCitations "yes".
- PSMD8 updatePage "yes".
- PSMD8 updateProteinBox "yes".
- PSMD8 updateSummary "yes".
- PSMD8 type Biomolecule.
- PSMD8 type Protein.
- PSMD8 type BiologicalObject.
- PSMD8 comment "26S proteasome non-ATPase regulatory subunit 8 is an enzyme that in humans is encoded by the PSMD8 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMD8 label "PSMD8".
- PSMD8 sameAs PSMD8.
- PSMD8 sameAs m.03gwsk7.
- PSMD8 sameAs Q7120724.
- PSMD8 sameAs Q7120724.
- PSMD8 wasDerivedFrom PSMD8?oldid=592872374.
- PSMD8 isPrimaryTopicOf PSMD8.