Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSME1> ?p ?o. }
Showing items 1 to 21 of
21
with 100 items per page.
- PSME1 abstract "Proteasome activator complex subunit 1 is a protein that in humans is encoded by the PSME1 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Two transcripts encoding different isoforms have been identified.".
- PSME1 entrezgene "5720".
- PSME1 wikiPageID "14726054".
- PSME1 wikiPageRevisionID "592872413".
- PSME1 hasPhotoCollection PSME1.
- PSME1 requireManualInspection "no".
- PSME1 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Two transcripts encoding different isoforms have been identified.".
- PSME1 updateCitations "yes".
- PSME1 updatePage "yes".
- PSME1 updateProteinBox "yes".
- PSME1 updateSummary "yes".
- PSME1 type Biomolecule.
- PSME1 type Protein.
- PSME1 type BiologicalObject.
- PSME1 comment "Proteasome activator complex subunit 1 is a protein that in humans is encoded by the PSME1 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSME1 label "PSME1".
- PSME1 sameAs m.03gvpw6.
- PSME1 sameAs Q7120726.
- PSME1 sameAs Q7120726.
- PSME1 wasDerivedFrom PSME1?oldid=592872413.
- PSME1 isPrimaryTopicOf PSME1.