Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PSMF1> ?p ?o. }
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- PSMF1 abstract "Proteasome inhibitor PI31 subunit is a protein that in humans is encoded by the PSMF1 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.".
- PSMF1 entrezgene "9491".
- PSMF1 wikiPageID "14754503".
- PSMF1 wikiPageRevisionID "601783811".
- PSMF1 hasPhotoCollection PSMF1.
- PSMF1 requireManualInspection "no".
- PSMF1 summaryText "The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.".
- PSMF1 updateCitations "yes".
- PSMF1 updatePage "yes".
- PSMF1 updateProteinBox "yes".
- PSMF1 updateSummary "yes".
- PSMF1 type Biomolecule.
- PSMF1 type Protein.
- PSMF1 type BiologicalObject.
- PSMF1 comment "Proteasome inhibitor PI31 subunit is a protein that in humans is encoded by the PSMF1 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.".
- PSMF1 label "PSMF1".
- PSMF1 sameAs m.03gwr6t.
- PSMF1 sameAs Q7120730.
- PSMF1 sameAs Q7120730.
- PSMF1 wasDerivedFrom PSMF1?oldid=601783811.
- PSMF1 isPrimaryTopicOf PSMF1.