Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PTPRB> ?p ?o. }
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- PTPRB abstract "Receptor-type tyrosine-protein phosphatase beta is an enzyme that in humans is encoded by the PTPRB gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation.".
- PTPRB entrezgene "5787".
- PTPRB wikiPageID "14771956".
- PTPRB wikiPageRevisionID "592875512".
- PTPRB hasPhotoCollection PTPRB.
- PTPRB requireManualInspection "no".
- PTPRB summaryText "The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation.".
- PTPRB updateCitations "yes".
- PTPRB updatePage "yes".
- PTPRB updateProteinBox "yes".
- PTPRB updateSummary "yes".
- PTPRB type Biomolecule.
- PTPRB type Protein.
- PTPRB type BiologicalObject.
- PTPRB comment "Receptor-type tyrosine-protein phosphatase beta is an enzyme that in humans is encoded by the PTPRB gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.".
- PTPRB label "PTPRB".
- PTPRB sameAs m.03gxgs9.
- PTPRB sameAs Q7121011.
- PTPRB sameAs Q7121011.
- PTPRB wasDerivedFrom PTPRB?oldid=592875512.
- PTPRB isPrimaryTopicOf PTPRB.