Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PTPRJ> ?p ?o. }
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- PTPRJ abstract "Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This PTP is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 (PLCG1) and Linker for Activation of T Cells (LAT). This PTP was also found to dephosphorylate PDGF beta receptor, and may be involved in UV-induced signal transduction.".
- PTPRJ entrezgene "5795".
- PTPRJ wikiPageID "14763230".
- PTPRJ wikiPageRevisionID "592875610".
- PTPRJ hasPhotoCollection PTPRJ.
- PTPRJ requireManualInspection "no".
- PTPRJ summaryText "The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This PTP is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells . This PTP was also found to dephosphorylate PDGF beta receptor, and may be involved in UV-induced signal transduction.".
- PTPRJ updateCitations "yes".
- PTPRJ updatePage "yes".
- PTPRJ updateProteinBox "yes".
- PTPRJ updateSummary "yes".
- PTPRJ type Biomolecule.
- PTPRJ type Protein.
- PTPRJ type BiologicalObject.
- PTPRJ comment "Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.".
- PTPRJ label "PTPRJ".
- PTPRJ sameAs m.03gx50d.
- PTPRJ sameAs Q7121018.
- PTPRJ sameAs Q7121018.
- PTPRJ sameAs PTPRJ.
- PTPRJ wasDerivedFrom PTPRJ?oldid=592875610.
- PTPRJ isPrimaryTopicOf PTPRJ.