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- Par_stability_determinant abstract "The par stability determinant is a 400 bp locus of the pAD1 plasmid which encodes a type I toxin-antitoxin system in Enterococcus faecalis. It was the first such plasmid addiction module to be found in gram-positive bacteria.The par locus contains two genes: fst which encodes a 33-amino acid toxic protein and a gene for RNAII, the small RNA anti-toxin which inhibits fst translation. The two genes are found on opposite DNA strands and share a 5' region which is where they are thought to have an antisense interaction. Their RNA secondary structures have been predicted computationally, the complementary regions appear to be presented on exposed loops for interaction.par maintains pAD1 by means of post-segregational killing (PSK). If a daughter cell does not inherit the par locus, the unstable RNAII will quickly degrade leaving the long-lived fst toxin to damage or kill the daughter cell.".
- Par_stability_determinant symbol "Fst_toxin".
- Par_stability_determinant thumbnail FstAT_SScons.png?width=300.
- Par_stability_determinant wikiPageExternalLink annurev.genet.31.1.1?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dncbi.nlm.nih.gov.
- Par_stability_determinant wikiPageExternalLink pmidlookup?view=long&pmid=3517851.
- Par_stability_determinant wikiPageExternalLink pmidlookup?view=long&pmid=12970556.
- Par_stability_determinant wikiPageID "28889735".
- Par_stability_determinant wikiPageRevisionID "592744414".
- Par_stability_determinant caption "Secondary structure of RNAII".
- Par_stability_determinant hasPhotoCollection Par_stability_determinant.
- Par_stability_determinant id "RF01797".
- Par_stability_determinant name "Fst Type I toxin-antitoxin system".
- Par_stability_determinant name "RNAII".
- Par_stability_determinant name "fst antitoxin sRNA".
- Par_stability_determinant pfam "PF13955".
- Par_stability_determinant rfam "RF01797".
- Par_stability_determinant rnaType Gene.
- Par_stability_determinant rnaType Toxin-antitoxin_system.
- Par_stability_determinant symbol "Fst_toxin".
- Par_stability_determinant symbol "fstAT".
- Par_stability_determinant taxDomain "Enterococcus faecalis".
- Par_stability_determinant subject Category:Antisense_RNA.
- Par_stability_determinant subject Category:RNA_antitoxins.
- Par_stability_determinant type Abstraction100002137.
- Par_stability_determinant type Antibody115027189.
- Par_stability_determinant type Antitoxin115028050.
- Par_stability_determinant type Chemical114806838.
- Par_stability_determinant type Compound114818238.
- Par_stability_determinant type Macromolecule114944888.
- Par_stability_determinant type Material114580897.
- Par_stability_determinant type Matter100020827.
- Par_stability_determinant type Molecule114682133.
- Par_stability_determinant type OrganicCompound114727670.
- Par_stability_determinant type Part113809207.
- Par_stability_determinant type PhysicalEntity100001930.
- Par_stability_determinant type Protein114728724.
- Par_stability_determinant type RNAAntitoxins.
- Par_stability_determinant type Relation100031921.
- Par_stability_determinant type Substance100019613.
- Par_stability_determinant type Thing100002452.
- Par_stability_determinant type Unit109465459.
- Par_stability_determinant type Biomolecule.
- Par_stability_determinant type Protein.
- Par_stability_determinant type BiologicalObject.
- Par_stability_determinant comment "The par stability determinant is a 400 bp locus of the pAD1 plasmid which encodes a type I toxin-antitoxin system in Enterococcus faecalis. It was the first such plasmid addiction module to be found in gram-positive bacteria.The par locus contains two genes: fst which encodes a 33-amino acid toxic protein and a gene for RNAII, the small RNA anti-toxin which inhibits fst translation.".
- Par_stability_determinant label "Par stability determinant".
- Par_stability_determinant sameAs m.0ddczwd.
- Par_stability_determinant sameAs Q7133609.
- Par_stability_determinant sameAs Q7133609.
- Par_stability_determinant sameAs Par_stability_determinant.
- Par_stability_determinant wasDerivedFrom Par_stability_determinant?oldid=592744414.
- Par_stability_determinant depiction FstAT_SScons.png.
- Par_stability_determinant isPrimaryTopicOf Par_stability_determinant.
