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- Partition_coefficient abstract "In the physical sciences, a partition- or distribution-coefficient is the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium. These coefficients are a measure of the difference in solubility of the compound in these two phases.In the chemical and pharmaceutical sciences, the two phases are often restricted to mean two immiscible solvents. In this context, a partition coefficient is the ratio of concentrations of a compound in the two phases of a mixture of two immiscible liquids at equilibrium. Normally one of the solvents chosen is water while the second is hydrophobic such as 1-octanol. Hence both the partition and distribution coefficient are measures of how hydrophilic ("water-loving") or hydrophobic ("water-fearing") a chemical substance is. In medical practice, partition coefficients are useful for example in estimating distribution of drugs within the body. Hydrophobic drugs with high octanol/water partition coefficients are preferentially distributed to hydrophobic compartments such as lipid bilayers of cells while hydrophilic drugs (low octanol/water partition coefficients) preferentially are found in hydrophilic compartments such as blood serum.If one of the solvents is a gas and the other a liquid, the "gas/liquid partition coefficient" is the same as the dimensionless form of the Henry's law constant. For example, the blood/gas partition coefficient of a general anesthetic measures how easily the anesthetic passes from gas to blood. Partition coefficients can also be used when one or both solvents is a solid (see solid solution).The phrase "partition coefficient" is now considered obsolete by IUPAC, and "partition constant", "partition ratio", or "distribution ratio" are all more appropriate terms that should be used.".
- Partition_coefficient wikiPageExternalLink bioloom.html.
- Partition_coefficient wikiPageExternalLink preadmet.bmdrc.org.
- Partition_coefficient wikiPageExternalLink freelogp.
- Partition_coefficient wikiPageExternalLink logp.
- Partition_coefficient wikiPageExternalLink index.html.
- Partition_coefficient wikiPageExternalLink properties.
- Partition_coefficient wikiPageExternalLink peo.
- Partition_coefficient wikiPageExternalLink Definitions.aspx?lID=59&pID=13.
- Partition_coefficient wikiPageExternalLink ?p=42&software=xlogp3.
- Partition_coefficient wikiPageExternalLink alogps.
- Partition_coefficient wikiPageExternalLink online.html.
- Partition_coefficient wikiPageID "796652".
- Partition_coefficient wikiPageRevisionID "605460915".
- Partition_coefficient hasPhotoCollection Partition_coefficient.
- Partition_coefficient subject Category:Equilibrium_chemistry.
- Partition_coefficient subject Category:Medicinal_chemistry.
- Partition_coefficient subject Category:Solvents.
- Partition_coefficient type Abstraction100002137.
- Partition_coefficient type Matter100020827.
- Partition_coefficient type Medium114899152.
- Partition_coefficient type Part113809207.
- Partition_coefficient type PhysicalEntity100001930.
- Partition_coefficient type Relation100031921.
- Partition_coefficient type Solvent115047313.
- Partition_coefficient type Solvents.
- Partition_coefficient type Substance100019613.
- Partition_coefficient comment "In the physical sciences, a partition- or distribution-coefficient is the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium. These coefficients are a measure of the difference in solubility of the compound in these two phases.In the chemical and pharmaceutical sciences, the two phases are often restricted to mean two immiscible solvents.".
- Partition_coefficient label "Coefficiente di ripartizione (chimica)".
- Partition_coefficient label "Coeficiente de partição".
- Partition_coefficient label "Coeficiente de reparto".
- Partition_coefficient label "LogP".
- Partition_coefficient label "Oktanol-Wasser-Verteilungskoeffizient".
- Partition_coefficient label "Partition coefficient".
- Partition_coefficient label "Verdelingscoëfficiënt".
- Partition_coefficient label "Współczynnik podziału".
- Partition_coefficient label "معامل التوزيع".
- Partition_coefficient label "分配係数".
- Partition_coefficient label "分配系数".
- Partition_coefficient sameAs Oktanol-Wasser-Verteilungskoeffizient.
- Partition_coefficient sameAs Coeficiente_de_reparto.
- Partition_coefficient sameAs LogP.
- Partition_coefficient sameAs Coefficiente_di_ripartizione_(chimica).
- Partition_coefficient sameAs 分配係数.
- Partition_coefficient sameAs Verdelingscoëfficiënt.
- Partition_coefficient sameAs Współczynnik_podziału.
- Partition_coefficient sameAs Coeficiente_de_partição.
- Partition_coefficient sameAs m.03cr_x.
- Partition_coefficient sameAs Q898797.
- Partition_coefficient sameAs Q898797.
- Partition_coefficient sameAs Partition_coefficient.
- Partition_coefficient wasDerivedFrom Partition_coefficient?oldid=605460915.
- Partition_coefficient isPrimaryTopicOf Partition_coefficient.