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- PelB_leader_sequence abstract "The pelB leader sequence is a sequence of amino acids which when attached to a protein, directs the protein to the bacterial periplasm, where the sequence is removed by a signal peptidase. Specifically, pelB refers to pectate lyase B of Erwinia carotovora CE. The leader sequence consists of the 22 N-terminal amino acid residues. This leader sequence can be attached to any other protein (on the DNA level) resulting in a transfer of such a fused protein to the periplasmic space of Gram-negative bacteria, such as Escherichia coli, often used in genetic engineering.protein secretion can increase the stability of cloned gene products.For instance it was shown that the half-life of the recombinant proinsulin is increased 10-fold when the protein is secreted to the periplasmic space. (vijji.Narne, R.S.Ramya)One of possible applications is to direct coat protein-antigen fusions to the cell surface for construction of engineered bacteriophage for the purpose of phage display. SP Lei et al., Characterization of the Erwinia carotovora pelB gene and its product pectate lyase. J. Bacteriol. 169(9): 4379–4383 (1987).".
- PelB_leader_sequence wikiPageExternalLink PMC213756.
- PelB_leader_sequence wikiPageID "3762839".
- PelB_leader_sequence wikiPageRevisionID "599283253".
- PelB_leader_sequence hasPhotoCollection PelB_leader_sequence.
- PelB_leader_sequence subject Category:Amino_acids.
- PelB_leader_sequence subject Category:Bacteria.
- PelB_leader_sequence subject Category:Genetic_engineering.
- PelB_leader_sequence type Abstraction100002137.
- PelB_leader_sequence type AminoAcid114601829.
- PelB_leader_sequence type AminoAcids.
- PelB_leader_sequence type Chemical114806838.
- PelB_leader_sequence type Compound114818238.
- PelB_leader_sequence type Material114580897.
- PelB_leader_sequence type Matter100020827.
- PelB_leader_sequence type OrganicCompound114727670.
- PelB_leader_sequence type Part113809207.
- PelB_leader_sequence type PhysicalEntity100001930.
- PelB_leader_sequence type Relation100031921.
- PelB_leader_sequence type Substance100019613.
- PelB_leader_sequence comment "The pelB leader sequence is a sequence of amino acids which when attached to a protein, directs the protein to the bacterial periplasm, where the sequence is removed by a signal peptidase. Specifically, pelB refers to pectate lyase B of Erwinia carotovora CE. The leader sequence consists of the 22 N-terminal amino acid residues.".
- PelB_leader_sequence label "PelB leader sequence".
- PelB_leader_sequence sameAs m.09znxt.
- PelB_leader_sequence sameAs Q7161128.
- PelB_leader_sequence sameAs Q7161128.
- PelB_leader_sequence sameAs PelB_leader_sequence.
- PelB_leader_sequence wasDerivedFrom PelB_leader_sequence?oldid=599283253.
- PelB_leader_sequence isPrimaryTopicOf PelB_leader_sequence.