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- Perifosine abstract "Perifosine (also KRX-0401) is a drug candidate being developed for a variety of cancer indications.It is an alkylphospholipid (octadecyl-(1,1-dimethyl-4-piperidylio) phosphate) Perifosine is structurally related to miltefosine. It acts as an Akt inhibitor and a PI3K inhibitor.It was being developed by Keryx Biopharmaceuticals who have licenced it from Æterna Zentaris Inc.In 2010 perifosine has reached phase II. In one phase II trial for metastatic colon cancer perifosine doubled time to progression.It has orphan drug status in the U.S. for the treatment of multiple myeloma and neuroblastoma, and for multiple myeloma in the EU.In 2011 it was in a phase III trial for colorectal cancer, and another for multiple myeloma. On April 2, 2012, it was announced that perifosine failed its phase III clinical trial for treatment of colon cancer. Detailed results were released in June 2012. On March 11, 2013 Aeterna Zentaris announced the discontinuing of Phase 3 clinical trial of perifosine for the treatment of relapsed and refractory multiple myeloma http://www.aezsinc.com/en/page.php?p=60&q=550.".
- Perifosine fdaUniiCode "2GWV496552".
- Perifosine iupacName "1,1-Dimethylpiperidinium-4-yl octadecyl phosphate".
- Perifosine thumbnail Perifosine.svg?width=300.
- Perifosine wikiPageExternalLink page.php?p=60&q=550..
- Perifosine wikiPageID "31032459".
- Perifosine wikiPageRevisionID "593400348".
- Perifosine hasPhotoCollection Perifosine.
- Perifosine imagefile "Perifosine.svg".
- Perifosine imagesize "250".
- Perifosine iupacname "11".
- Perifosine othernames "D 21266; KRX 0401".
- Perifosine unii "2".
- Perifosine subject Category:Organophosphates.
- Perifosine subject Category:Phosphoinositide_3-kinase_inhibitors.
- Perifosine subject Category:Quaternary_ammonium_compounds.
- Perifosine subject Category:Zwitterions.
- Perifosine type Abstraction100002137.
- Perifosine type Chemical114806838.
- Perifosine type Compound114818238.
- Perifosine type Insecticide114919948.
- Perifosine type Material114580897.
- Perifosine type Matter100020827.
- Perifosine type OrganicCompound114727670.
- Perifosine type Organophosphate114969994.
- Perifosine type Organophosphates.
- Perifosine type Part113809207.
- Perifosine type Pesticide114980215.
- Perifosine type PhysicalEntity100001930.
- Perifosine type QuaternaryAmmoniumCompound114691231.
- Perifosine type QuaternaryAmmoniumCompounds.
- Perifosine type Relation100031921.
- Perifosine type Substance100019613.
- Perifosine type ChemicalCompound.
- Perifosine type ChemicalSubstance.
- Perifosine type ChemicalObject.
- Perifosine type Thing.
- Perifosine comment "Perifosine (also KRX-0401) is a drug candidate being developed for a variety of cancer indications.It is an alkylphospholipid (octadecyl-(1,1-dimethyl-4-piperidylio) phosphate) Perifosine is structurally related to miltefosine. It acts as an Akt inhibitor and a PI3K inhibitor.It was being developed by Keryx Biopharmaceuticals who have licenced it from Æterna Zentaris Inc.In 2010 perifosine has reached phase II.".
- Perifosine label "Perifosine".
- Perifosine label "Périfosine".
- Perifosine sameAs Périfosine.
- Perifosine sameAs m.0gg9fv_.
- Perifosine sameAs Q3411917.
- Perifosine sameAs Q3411917.
- Perifosine sameAs Perifosine.
- Perifosine wasDerivedFrom Perifosine?oldid=593400348.
- Perifosine depiction Perifosine.svg.
- Perifosine isPrimaryTopicOf Perifosine.
