Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Pethidine> ?p ?o. }
- Pethidine abstract "Pethidine (INN, AAN, BAN) or meperidine (USAN) is a once popular synthetic opioid analgesic of the phenylpiperidine class. Synthesized in 1939 as a potential anticholinergic agent by the German chemist Otto Eislib, its analgesic properties were first recognized by Otto Schaumann while working for IG Farben, Germany.Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975 60% of doctors prescribed it for acute pain and 22% for chronic severe pain.Compared to morphine, pethidine was thought to be safer, carry a lower risk of addiction and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. It was later discovered that these were all myths and that it carried an at least equal risk of addiction, possessed no advantageous effects on biliary spasm or renal colic compared to other opioids and that, due to its toxic metabolite, norpethidine, it was more toxic than other opioids, especially during long-term use. It was also discovered that the norpethidine metabolite had serotonergic effects which means that pethidine could, unlike most opioids, contribute to serotonin syndrome.".
- Pethidine atcPrefix "N02".
- Pethidine atcSuffix "AB02".
- Pethidine bioavailability "50.0".
- Pethidine casNumber "57-42-1".
- Pethidine drugbank "DB00454".
- Pethidine fdaUniiCode "9E338QE28F".
- Pethidine iupacName "Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate".
- Pethidine pubchem "4058".
- Pethidine thumbnail Pethidine2DACS.svg?width=300.
- Pethidine wikiPageID "617611".
- Pethidine wikiPageRevisionID "605450840".
- Pethidine atcPrefix "N02".
- Pethidine atcSuffix "AB02".
- Pethidine bioavailability "50".
- Pethidine c "15".
- Pethidine casNumber "57".
- Pethidine chembl "607".
- Pethidine chemspiderid "3918".
- Pethidine dependenceLiability "High".
- Pethidine drugbank "DB00454".
- Pethidine eliminationHalfLife "-39600.0".
- Pethidine excretion "Renal".
- Pethidine h "21".
- Pethidine hasPhotoCollection Pethidine.
- Pethidine image "Pethidine3DanBS.gif".
- Pethidine inchi "1".
- Pethidine inchikey "XADCESSVHJOZHK-UHFFFAOYAY".
- Pethidine iupacName "Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate".
- Pethidine kegg "D08343".
- Pethidine legalAu "S8".
- Pethidine legalCa "Schedule I".
- Pethidine legalStatus "Class B3".
- Pethidine legalUk "Class A".
- Pethidine legalUs "Schedule II".
- Pethidine metabolism Liver.
- Pethidine molecularWeight "247.33".
- Pethidine n "1".
- Pethidine o "2".
- Pethidine pregnancyAu "C".
- Pethidine pregnancyUs "C".
- Pethidine proteinBound "65".
- Pethidine pubchem "4058".
- Pethidine routesOfAdministration "oral, intravenous, intramuscular, subcutaneous".
- Pethidine smiles "O=COCC".
- Pethidine stdinchi "1".
- Pethidine stdinchiRef "=".
- Pethidine stdinchikey "XADCESSVHJOZHK-UHFFFAOYSA-N".
- Pethidine stdinchikeyRef "=".
- Pethidine tradename "Demerol".
- Pethidine unii "Infinity".
- Pethidine verifiedrevid "464199592".
- Pethidine watchedfields "changed".
- Pethidine width "100".
- Pethidine width "150".
- Pethidine subject Category:Analgesics.
- Pethidine subject Category:Convulsants.
- Pethidine subject Category:Dopamine_reuptake_inhibitors.
- Pethidine subject Category:Ethyl_esters.
- Pethidine subject Category:Euphoriants.
- Pethidine subject Category:Local_anesthetics.
- Pethidine subject Category:Mu-opioid_agonists.
- Pethidine subject Category:Norepinephrine_reuptake_inhibitors.
- Pethidine subject Category:Piperidines.
- Pethidine subject Category:Synthetic_opioids.
- Pethidine type Agent114778436.
- Pethidine type Analgesic102707683.
- Pethidine type Analgesics.
- Pethidine type CausalAgent100007347.
- Pethidine type DopamineReuptakeInhibitors.
- Pethidine type Drug103247620.
- Pethidine type Drugs.
- Pethidine type Euphoriant103301696.
- Pethidine type Euphoriants.
- Pethidine type Inhibitor114724436.
- Pethidine type Matter100020827.
- Pethidine type Medicine103740161.
- Pethidine type NorepinephrineReuptakeInhibitors.
- Pethidine type PhysicalEntity100001930.
- Pethidine type PsychoactiveDrug104017137.
- Pethidine type Substance100020090.
- Pethidine type Drug.
- Pethidine type DrugProduct.
- Pethidine type FunctionalSubstance.
- Pethidine comment "Pethidine (INN, AAN, BAN) or meperidine (USAN) is a once popular synthetic opioid analgesic of the phenylpiperidine class.".
- Pethidine label "Pethidin".
- Pethidine label "Pethidine".
- Pethidine label "Pethidine".
- Pethidine label "Petidina".
- Pethidine label "Petidina".
- Pethidine label "Petidina".
- Pethidine label "Petydyna".
- Pethidine label "Péthidine".
- Pethidine label "Петидин".
- Pethidine label "بيثيدين".
- Pethidine label "ペチジン".
- Pethidine label "哌替啶".
- Pethidine sameAs Meperidin.
- Pethidine sameAs Pethidin.
- Pethidine sameAs Πεθιδίνη.
