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- Pocock_boundary abstract "The Pocock boundary is a method for determining whether to stop a clinical trial prematurely. The typical clinical trial compares two groups of patients. One group are given a placebo or conventional treatment, while the other group of patients are given the treatment that is being tested. The investigators running the clinical trial will wish to stop the trial early for ethical reasons if the treatment group clearly shows evidence of benefit. In other words, "when early results proved so promising it was no longer fair to keep patients on the older drugs for comparison, without giving them the opportunity to change."The concept was introduced by the medical statistician Stuart Pocock in 1977. The many reasons underlying when to stop a clinical trial for benefit were discussed in an editorial from his hand in 2005.".
- Pocock_boundary wikiPageID "27668861".
- Pocock_boundary wikiPageRevisionID "588146131".
- Pocock_boundary hasPhotoCollection Pocock_boundary.
- Pocock_boundary subject Category:Clinical_research.
- Pocock_boundary subject Category:Design_of_experiments.
- Pocock_boundary subject Category:Sequential_experiments.
- Pocock_boundary subject Category:Statistical_methods.
- Pocock_boundary type Ability105616246.
- Pocock_boundary type Abstraction100002137.
- Pocock_boundary type Act100030358.
- Pocock_boundary type Activity100407535.
- Pocock_boundary type Cognition100023271.
- Pocock_boundary type Event100029378.
- Pocock_boundary type Experiment100639556.
- Pocock_boundary type Investigation100633864.
- Pocock_boundary type Know-how105616786.
- Pocock_boundary type Method105660268.
- Pocock_boundary type PsychologicalFeature100023100.
- Pocock_boundary type Research100636921.
- Pocock_boundary type ScientificResearch100641820.
- Pocock_boundary type SequentialExperiments.
- Pocock_boundary type StatisticalMethod106020737.
- Pocock_boundary type StatisticalMethods.
- Pocock_boundary type Work100575741.
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- Pocock_boundary comment "The Pocock boundary is a method for determining whether to stop a clinical trial prematurely. The typical clinical trial compares two groups of patients. One group are given a placebo or conventional treatment, while the other group of patients are given the treatment that is being tested. The investigators running the clinical trial will wish to stop the trial early for ethical reasons if the treatment group clearly shows evidence of benefit.".
- Pocock_boundary label "Pocock boundary".
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- Pocock_boundary sameAs Q7206501.
- Pocock_boundary sameAs Q7206501.
- Pocock_boundary sameAs Pocock_boundary.
- Pocock_boundary wasDerivedFrom Pocock_boundary?oldid=588146131.
- Pocock_boundary isPrimaryTopicOf Pocock_boundary.