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- Polyglutamine_tract abstract "A polyglutamine tract or polyQ tract is a portion of a protein consisting of a sequence of several glutamine units. A tract typically consists of about 10 to a few hundred such units. A multitude of genes, in various eukaryotic species (including humans), contain a number of repetitions of the nucleotide triplet CAG or CAA. When the gene is translated into a protein, each of these triplets gives rise to a glutamine unit, resulting in a polyglutamine tract. Different alleles of such a gene often have different numbers of triplets since the highly repetitive sequence is prone to contraction and expansion. Several inheritable neurodegenerative disorders, the polyglutamine diseases, occur if a mutation causes a polyglutamine tract in a specific gene to become too long. Important examples of polyglutamine diseases are spinocerebellar ataxia and Huntington's disease. It is believed that cells cannot properly dispose of proteins with overly long polyglutamine tracts, which over time leads to damage in nerve cells. The longer the polyglutamine tract, the earlier in life these diseases tend to appear.".
- Polyglutamine_tract wikiPageID "20895673".
- Polyglutamine_tract wikiPageRevisionID "564843345".
- Polyglutamine_tract hasPhotoCollection Polyglutamine_tract.
- Polyglutamine_tract subject Category:Peptides.
- Polyglutamine_tract type Abstraction100002137.
- Polyglutamine_tract type Amide114724264.
- Polyglutamine_tract type Chemical114806838.
- Polyglutamine_tract type Compound114818238.
- Polyglutamine_tract type Material114580897.
- Polyglutamine_tract type Matter100020827.
- Polyglutamine_tract type OrganicCompound114727670.
- Polyglutamine_tract type Part113809207.
- Polyglutamine_tract type Peptide114743046.
- Polyglutamine_tract type Peptides.
- Polyglutamine_tract type PhysicalEntity100001930.
- Polyglutamine_tract type Relation100031921.
- Polyglutamine_tract type Substance100019613.
- Polyglutamine_tract comment "A polyglutamine tract or polyQ tract is a portion of a protein consisting of a sequence of several glutamine units. A tract typically consists of about 10 to a few hundred such units. A multitude of genes, in various eukaryotic species (including humans), contain a number of repetitions of the nucleotide triplet CAG or CAA. When the gene is translated into a protein, each of these triplets gives rise to a glutamine unit, resulting in a polyglutamine tract.".
- Polyglutamine_tract label "Polyglutamine tract".
- Polyglutamine_tract sameAs m.05b026z.
- Polyglutamine_tract sameAs Q7226416.
- Polyglutamine_tract sameAs Q7226416.
- Polyglutamine_tract sameAs Polyglutamine_tract.
- Polyglutamine_tract wasDerivedFrom Polyglutamine_tract?oldid=564843345.
- Polyglutamine_tract isPrimaryTopicOf Polyglutamine_tract.