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- Posttranslational_modification abstract "Posttranslational modification (PTM) is a step in protein biosynthesis. Proteins are created by ribosomes translating mRNA into polypeptide chains. These polypeptide chains undergo PTM (such as folding, cutting and other processes) before becoming the mature protein product.A protein (also called a polypeptide) is a chain of amino acids. During protein synthesis, 20 different amino acids can be incorporated to become a protein. After translation, the posttranslational modification of amino acids extends the range of functions of the protein by attaching it to other biochemical functional groups (such as acetate, phosphate, various lipids and carbohydrates), changing the chemical nature of an amino acid (e.g. citrullination), or making structural changes (e.g. formation of disulfide bridges).Also, enzymes may remove amino acids from the amino end of the protein, or cut the peptide chain in the middle. For instance, the peptide hormone insulin is cut twice after disulfide bonds are formed, and a propeptide is removed from the middle of the chain; the resulting protein consists of two polypeptide chains connected by disulfide bonds. Also, most nascent polypeptides start with the amino acid methionine because the "start" codon on mRNA also codes for this amino acid. This amino acid is usually taken off during post-translational modification.Other modifications, like phosphorylation, are part of common mechanisms for controlling the behavior of a protein, for instance activating or inactivating an enzyme.Post-translational modification of proteins can be detected by a variety of techniques, including mass spectrometry, Eastern blotting, and Western blotting.".
- Posttranslational_modification thumbnail Insulinpath.png?width=300.
- Posttranslational_modification wikiPageExternalLink ams2.bioinfo.pl.
- Posttranslational_modification wikiPageExternalLink ams3.bioinfo.pl.
- Posttranslational_modification wikiPageExternalLink dbptm.mbc.nctu.edu.tw.
- Posttranslational_modification wikiPageExternalLink PTMCuration.
- Posttranslational_modification wikiPageExternalLink dcbo.cgi?type=KW;po=9991.
- Posttranslational_modification wikiPageExternalLink deltaMasses.html.
- Posttranslational_modification wikiPageExternalLink functional_analyses_for_sitesp.php.
- Posttranslational_modification wikiPageExternalLink automotif_server_a_computation.php.
- Posttranslational_modification wikiPageExternalLink 1tp8.
- Posttranslational_modification wikiPageExternalLink ptmlist.
- Posttranslational_modification wikiPageID "164901".
- Posttranslational_modification wikiPageRevisionID "602797575".
- Posttranslational_modification hasPhotoCollection Posttranslational_modification.
- Posttranslational_modification subject Category:Cell_biology.
- Posttranslational_modification subject Category:Gene_expression.
- Posttranslational_modification subject Category:Posttranslational_modification.
- Posttranslational_modification subject Category:Protein_biosynthesis.
- Posttranslational_modification subject Category:Protein_structure.
- Posttranslational_modification comment "Posttranslational modification (PTM) is a step in protein biosynthesis. Proteins are created by ribosomes translating mRNA into polypeptide chains. These polypeptide chains undergo PTM (such as folding, cutting and other processes) before becoming the mature protein product.A protein (also called a polypeptide) is a chain of amino acids. During protein synthesis, 20 different amino acids can be incorporated to become a protein.".
- Posttranslational_modification label "Modificación postraduccional".
- Posttranslational_modification label "Modification post-traductionnelle".
- Posttranslational_modification label "Modificazione post traduzionale".
- Posttranslational_modification label "Modificação pós-traducional".
- Posttranslational_modification label "Modyfikacje posttranslacyjne".
- Posttranslational_modification label "Posttranslational modification".
- Posttranslational_modification label "Posttranslationale Modifikation".
- Posttranslational_modification label "Posttranslationele modificatie".
- Posttranslational_modification label "Посттрансляционная модификация".
- Posttranslational_modification label "翻訳後修飾".
- Posttranslational_modification label "翻译后修饰".
- Posttranslational_modification sameAs Posttranslační_modifikace.
- Posttranslational_modification sameAs Posttranslationale_Modifikation.
- Posttranslational_modification sameAs Modificación_postraduccional.
- Posttranslational_modification sameAs Modification_post-traductionnelle.
- Posttranslational_modification sameAs Modificazione_post_traduzionale.
- Posttranslational_modification sameAs 翻訳後修飾.
- Posttranslational_modification sameAs Posttranslationele_modificatie.
- Posttranslational_modification sameAs Modyfikacje_posttranslacyjne.
- Posttranslational_modification sameAs Modificação_pós-traducional.
- Posttranslational_modification sameAs m.015z32.
- Posttranslational_modification sameAs Q898362.
- Posttranslational_modification sameAs Q898362.
- Posttranslational_modification wasDerivedFrom Posttranslational_modification?oldid=602797575.
- Posttranslational_modification depiction Insulinpath.png.
- Posttranslational_modification isPrimaryTopicOf Posttranslational_modification.
