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- Potentiator abstract "In clinical terms, a potentiator is a reagent that enhances sensitization of an antigen. Potentiators are used in the clinical laboratory for performing blood banking procedures that require enhancement of Agglutination (biology) in order to detect the presence of antibodies or antigens in a patient's blood sample. Examples of potentiators include albumin, LISS (low ionic-strength saline) and PEG (polyethylene glycol). Potentiators are also known as enhancement reagents.Albumin acts as a potentiator by reducing the zeta potential around the suspended red blood cells, thus dispersing the repulsive negative charges and enhancing agglutination. Low ionic strength saline is a potentiator that acts by not only reducing the zeta potential, but also by increasing the amount of antibody taken up by the red blood cell during sensitization. LISS is a solution of glycine and albumin. Polyethylene glycol in a LISS solution removes water from the system and thus concentrates the antibodies present. PEG can cause non-specific aggregation of cells, thus eliminating the necessity for centrifugation after 37°C incubation. PEG is not appropriate for use in samples from patients with increased plasma protein, such as patients with multiple myeloma. False-positive results may occur more frequently with the use of polyethylene glycol due to its strong agglutination capabilities.".
- Potentiator wikiPageID "9488884".
- Potentiator wikiPageRevisionID "541882173".
- Potentiator hasPhotoCollection Potentiator.
- Potentiator subject Category:Chemical_reactions.
- Potentiator subject Category:Reagents_for_organic_chemistry.
- Potentiator type Agent114778436.
- Potentiator type CausalAgent100007347.
- Potentiator type ChemicalAgent114779550.
- Potentiator type ChemicalProcess113446390.
- Potentiator type ChemicalReaction113447361.
- Potentiator type ChemicalReactions.
- Potentiator type Matter100020827.
- Potentiator type NaturalProcess113518963.
- Potentiator type PhysicalEntity100001930.
- Potentiator type Process100029677.
- Potentiator type Reagent114778982.
- Potentiator type ReagentsForOrganicChemistry.
- Potentiator type Substance100020090.
- Potentiator comment "In clinical terms, a potentiator is a reagent that enhances sensitization of an antigen. Potentiators are used in the clinical laboratory for performing blood banking procedures that require enhancement of Agglutination (biology) in order to detect the presence of antibodies or antigens in a patient's blood sample. Examples of potentiators include albumin, LISS (low ionic-strength saline) and PEG (polyethylene glycol).".
- Potentiator label "Potentiator".
- Potentiator sameAs m.028byy6.
- Potentiator sameAs Q7234839.
- Potentiator sameAs Q7234839.
- Potentiator sameAs Potentiator.
- Potentiator wasDerivedFrom Potentiator?oldid=541882173.
- Potentiator isPrimaryTopicOf Potentiator.