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- Pre-integration_complex abstract "The pre-integration complex (PIC) is a nucleoprotein complex of viral genetic material and associated viral and host proteins which is capable of inserting a viral genome into a host genome. The PIC forms after uncoating of a viral particle after entry into the host cell. In the case of the human immunodeficiency virus (HIV), the PIC forms after the Reverse Transcription Complex (RTC) has reverse transcribed the viral RNA code into DNA code. The PIC consists of viral proteins (including Vpr, matrix and integrase), host proteins (including Barrier to autointegration factor 1) and the viral DNA. The PIC enters the cellular nucleus through the nuclear pore complex without disrupting the nuclear envelope, thus allowing HIV and related retroviruses to replicate in non-dividing cells. Following nuclear entry, the PIC's DNA payload may be integrated into the host DNA as a "provirus".".
- Pre-integration_complex wikiPageExternalLink fulltextPDF?accountid=14214.
- Pre-integration_complex wikiPageExternalLink ?q=preintegration%20complex.
- Pre-integration_complex wikiPageID "16832751".
- Pre-integration_complex wikiPageRevisionID "563014899".
- Pre-integration_complex hasPhotoCollection Pre-integration_complex.
- Pre-integration_complex subject Category:Virology.
- Pre-integration_complex type Agent109190918.
- Pre-integration_complex type CausalAgent100007347.
- Pre-integration_complex type InfectiousAgent109312843.
- Pre-integration_complex type LivingThing100004258.
- Pre-integration_complex type Microorganism101326291.
- Pre-integration_complex type Object100002684.
- Pre-integration_complex type Organism100004475.
- Pre-integration_complex type PhysicalEntity100001930.
- Pre-integration_complex type Virus101328702.
- Pre-integration_complex type Viruses.
- Pre-integration_complex type Whole100003553.
- Pre-integration_complex comment "The pre-integration complex (PIC) is a nucleoprotein complex of viral genetic material and associated viral and host proteins which is capable of inserting a viral genome into a host genome. The PIC forms after uncoating of a viral particle after entry into the host cell. In the case of the human immunodeficiency virus (HIV), the PIC forms after the Reverse Transcription Complex (RTC) has reverse transcribed the viral RNA code into DNA code.".
- Pre-integration_complex label "Pre-integration complex".
- Pre-integration_complex sameAs m.0407s20.
- Pre-integration_complex sameAs Q7239240.
- Pre-integration_complex sameAs Q7239240.
- Pre-integration_complex sameAs Pre-integration_complex.
- Pre-integration_complex wasDerivedFrom Pre-integration_complex?oldid=563014899.
- Pre-integration_complex isPrimaryTopicOf Pre-integration_complex.