Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Prodine> ?p ?o. }
Showing items 1 to 51 of
51
with 100 items per page.
- Prodine abstract "Prodine (trade names Prisilidine and Nisentil) is an opioid analgesic that is an analog of pethidine (meperidine). There are two isomers of prodine, alphaprodine and betaprodine. Betaprodine is some 5x more potent than alphaprodine, but is metabolised more rapidly, and only alphaprodine was developed for medicinal use. It has similar activity to pethidine, but with a faster onset of action and shorter duration.Alphaprodine has a DEA ACSCN of 9010 and 2013 manufacturing quota of 3 grammes; betaprodine has an ACSCN of 9611 and a 2 gramme quota. Alphaprodine was sold under several brand names, mainly Nisentil and Prisilidine. It was mainly used for pain relief in childbirth and dentistry, as well as for minor surgical procedures. Alphaprodine has a duration of action of 1 to 2 hours and 40 to 60 mg is equal to 10 mg of morphine via the subcutaneous route.Prodine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening. Respiratory depression can be a problem with alphaprodine even at normal therapeutic doses. Unlike pethidine, prodine does not produce toxic metabolites and is therefore more suitable for high dose therapy.[medical citation needed]".
- Prodine atcPrefix "none".
- Prodine casNumber "77-20-3".
- Prodine casSupplemental "(beta)".
- Prodine iupacName "(1,3-Dimethyl-4-phenylpiperidin-4-yl) propanoate".
- Prodine pubchem "204163".
- Prodine thumbnail Alphaprodine.svg?width=300.
- Prodine wikiPageID "13853996".
- Prodine wikiPageRevisionID "606716008".
- Prodine atcPrefix "none".
- Prodine c "16".
- Prodine casNumber "77".
- Prodine chembl "14309".
- Prodine chemspiderid "176845".
- Prodine h "23".
- Prodine hasPhotoCollection Prodine.
- Prodine inchi "1".
- Prodine inchikey "UVAZQQHAVMNMHE-CJNGLKHVBH".
- Prodine iupacName "propanoate".
- Prodine legalAu "S8".
- Prodine legalUs "Schedule II".
- Prodine molecularWeight "261.359".
- Prodine n "1".
- Prodine o "2".
- Prodine pubchem "204163".
- Prodine smiles "O=CO[C@]1C2=CC=CC=C2".
- Prodine stdinchi "1".
- Prodine stdinchikey "UVAZQQHAVMNMHE-CJNGLKHVSA-N".
- Prodine verifiedfields "changed".
- Prodine verifiedrevid "464215177".
- Prodine watchedfields "changed".
- Prodine width "160".
- Prodine subject Category:Mu-opioid_agonists.
- Prodine subject Category:Opioids.
- Prodine subject Category:Piperidines.
- Prodine subject Category:Propionates.
- Prodine type Drug.
- Prodine type DrugProduct.
- Prodine type FunctionalSubstance.
- Prodine comment "Prodine (trade names Prisilidine and Nisentil) is an opioid analgesic that is an analog of pethidine (meperidine). There are two isomers of prodine, alphaprodine and betaprodine. Betaprodine is some 5x more potent than alphaprodine, but is metabolised more rapidly, and only alphaprodine was developed for medicinal use.".
- Prodine label "Prodine".
- Prodine label "Prodyna".
- Prodine label "Бетапродин".
- Prodine sameAs Prodyna.
- Prodine sameAs m.03cl949.
- Prodine sameAs Q4346433.
- Prodine sameAs Q4346433.
- Prodine sameAs DB01473.
- Prodine wasDerivedFrom Prodine?oldid=606716008.
- Prodine depiction Alphaprodine.svg.
- Prodine isPrimaryTopicOf Prodine.
