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- Prostaglandin_E2 abstract "The naturally occurring prostaglandin E2 (PGE2 or PGE2) is known in medicine as dinoprostone. It has important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts. PGE2 is also the prostaglandin that ultimately induces fever.It is sold under the trade name of Cervidil (by Forest Laboratories, Inc.), Prostin E2 (by Pfizer Inc.), Propess (by Ferring Pharmaceuticals) and Glandin (by Nabiqasim Pharmaceuticals Pakistan) as a vaginal suppository, to prepare the cervix for labour; it is used to induce labour.Like other prostaglandins, dinoprostone can be used as an abortifacient. It is a direct vasodilator, relaxing smooth muscles, and it inhibits the release of noradrenaline from sympathetic nerve terminals. It does not inhibit platelet aggregation, where PGI2 does.It works by binding and activating the prostaglandin E2 receptor.It was discovered by Bunting, Gryglewski, Moncada and Vane in 1976.Up-regulation of PGE2 has been implicated as a possible etiology of nail clubbing. It is also implicated in duct dependant congenital heart diseases and is used in infusion in order to open the duct.Precautions: uterine scar tissues; asthma; low blood pressure; heart disease; adrenal problems; anemia; diabetes; glaucoma; icterus (jaundice); multiparity (5 pregnancies); heart, lung or liver disease.".
- Prostaglandin_E2 atcPrefix "G02".
- Prostaglandin_E2 atcSuffix "AD02".
- Prostaglandin_E2 casNumber "363-24-6".
- Prostaglandin_E2 chEBI "15551".
- Prostaglandin_E2 drugbank "DB00917".
- Prostaglandin_E2 iupacName "(5Z,11α,13E,15S)-7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)- 5-oxo-cyclopentyl] hept-5-enoic acid".
- Prostaglandin_E2 pubchem "9691".
- Prostaglandin_E2 thumbnail Prostaglandin_E2.svg?width=300.
- Prostaglandin_E2 wikiPageExternalLink cervidil.html.
- Prostaglandin_E2 wikiPageExternalLink Cervidil.html.
- Prostaglandin_E2 wikiPageExternalLink cervidil.aspx.
- Prostaglandin_E2 wikiPageExternalLink a682512.html.
- Prostaglandin_E2 wikiPageExternalLink uspi_prostin.pdf.
- Prostaglandin_E2 wikiPageExternalLink dinoprostone.htm.
- Prostaglandin_E2 wikiPageID "3936671".
- Prostaglandin_E2 wikiPageRevisionID "598898038".
- Prostaglandin_E2 atcPrefix "G02".
- Prostaglandin_E2 atcSuffix "AD02".
- Prostaglandin_E2 c "20".
- Prostaglandin_E2 casNumber "363".
- Prostaglandin_E2 chebi "15551".
- Prostaglandin_E2 chembl "548".
- Prostaglandin_E2 drugbank "DB00917".
- Prostaglandin_E2 h "32".
- Prostaglandin_E2 hasPhotoCollection Prostaglandin_E2.
- Prostaglandin_E2 iupacName "-7".
- Prostaglandin_E2 iupharLigand "1883".
- Prostaglandin_E2 medlineplus "a682512".
- Prostaglandin_E2 molecularWeight "352.465".
- Prostaglandin_E2 o "5".
- Prostaglandin_E2 pubchem "9691".
- Prostaglandin_E2 synonyms "-1115".
- Prostaglandin_E2 verifiedfields "changed".
- Prostaglandin_E2 verifiedrevid "394516799".
- Prostaglandin_E2 watchedfields "changed".
- Prostaglandin_E2 subject Category:Abortifacients.
- Prostaglandin_E2 subject Category:Alcohols.
- Prostaglandin_E2 subject Category:Carboxylic_acids.
- Prostaglandin_E2 subject Category:Obstetric_drugs.
- Prostaglandin_E2 subject Category:Prostaglandins.
- Prostaglandin_E2 type Drug.
- Prostaglandin_E2 type DrugProduct.
- Prostaglandin_E2 type FunctionalSubstance.
- Prostaglandin_E2 comment "The naturally occurring prostaglandin E2 (PGE2 or PGE2) is known in medicine as dinoprostone. It has important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.".
- Prostaglandin_E2 label "Dinoproston".
- Prostaglandin_E2 label "Prostaglandin E2".
- Prostaglandin_E2 label "Prostaglandin E2".
- Prostaglandin_E2 label "Prostaglandina E2".
- Prostaglandin_E2 label "Prostaglandine E2".
- Prostaglandin_E2 label "ジノプロストン".
- Prostaglandin_E2 label "前列腺素E2".
- Prostaglandin_E2 sameAs Prostaglandin_E2.
- Prostaglandin_E2 sameAs Prostaglandine_E2.
- Prostaglandin_E2 sameAs ジノプロストン.
- Prostaglandin_E2 sameAs Dinoproston.
- Prostaglandin_E2 sameAs Prostaglandina_E2.
- Prostaglandin_E2 sameAs m.0b7m3s.
- Prostaglandin_E2 sameAs Q416554.
- Prostaglandin_E2 sameAs Q416554.
- Prostaglandin_E2 sameAs DB00917.
- Prostaglandin_E2 sameAs DB02304.
- Prostaglandin_E2 sameAs DB03866.
- Prostaglandin_E2 sameAs 158.
- Prostaglandin_E2 wasDerivedFrom Prostaglandin_E2?oldid=598898038.
- Prostaglandin_E2 depiction Prostaglandin_E2.svg.
- Prostaglandin_E2 isPrimaryTopicOf Prostaglandin_E2.
