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- Protein-bound_paclitaxel abstract "Protein-bound paclitaxel is an injectable formulation of paclitaxel, a mitotic inhibitor drug used in the treatment of breast cancer, lung cancer and pancreatic cancer. In this formulation, paclitaxel is bonded to albumin as a delivery vehicle. It is sometimes called nab-paclitaxel (with the "nab" syllable derived from "nanoparticle albumin–bound"). It is sold in the United States under the trade name Abraxane.This treatment was approved by the U.S. Food and Drug Administration (FDA) in January 2005 and the European Medicines Agency in January 2008 for breast cancer cases where cancer did not respond to other chemotherapy or has relapsed. In June 2010, positive results were published from a phase III trial in first-line non-small-cell lung cancer (NSCLC) when compared with solvent-based paclitaxel, and in October 2012 the FDA widened the approved use of Abraxane to include treatment for NSCLC. In September 2013, the FDA approved Abraxane for use in treating advanced pancreatic cancer as a less toxic (although less effective) alternative to FOLFIRINOXAbraxane is registered on the Australian Register of Therapeutic Goods for the treatment of metastatic carcinoma of the breast after failure of anthracycline therapy. Abraxane is also included on the Schedule of the Australian Pharmaceutical Benefits Scheme although the manufacturer was unable to convince the independent Pharmaceutical Benefits Advisory Committee that the drug warranted a higher price than existing comparator drugs.Abraxane was developed by Abraxis BioScience as the first in its class of drugs to use the nanoparticle albumin bound (nab) technology platform. In 2010, Abraxis was acquired by Celgene, which now markets Abraxane. Total revenue from the sales of Abraxane for 2009 were $314.5 million.".
- Protein-bound_paclitaxel wikiPageExternalLink articles.php?article_id=3077.
- Protein-bound_paclitaxel wikiPageID "12419027".
- Protein-bound_paclitaxel wikiPageRevisionID "588860725".
- Protein-bound_paclitaxel chemspiderid "NA".
- Protein-bound_paclitaxel class Mitotic_inhibitor.
- Protein-bound_paclitaxel class "Delivery vehicle".
- Protein-bound_paclitaxel component "Albumin".
- Protein-bound_paclitaxel component "Paclitaxel".
- Protein-bound_paclitaxel hasPhotoCollection Protein-bound_paclitaxel.
- Protein-bound_paclitaxel legalUs "Rx-only".
- Protein-bound_paclitaxel pregnancyUs "D".
- Protein-bound_paclitaxel routesOfAdministration Intravenous_therapy.
- Protein-bound_paclitaxel tradename "Abraxane".
- Protein-bound_paclitaxel type "combo".
- Protein-bound_paclitaxel verifiedfields "changed".
- Protein-bound_paclitaxel verifiedrevid "443693471".
- Protein-bound_paclitaxel subject Category:Breast_cancer.
- Protein-bound_paclitaxel subject Category:Mitotic_inhibitors.
- Protein-bound_paclitaxel type Inhibitor114724436.
- Protein-bound_paclitaxel type Matter100020827.
- Protein-bound_paclitaxel type MitoticInhibitors.
- Protein-bound_paclitaxel type PhysicalEntity100001930.
- Protein-bound_paclitaxel type Substance100020090.
- Protein-bound_paclitaxel type Drug.
- Protein-bound_paclitaxel type FunctionalSubstance.
- Protein-bound_paclitaxel comment "Protein-bound paclitaxel is an injectable formulation of paclitaxel, a mitotic inhibitor drug used in the treatment of breast cancer, lung cancer and pancreatic cancer. In this formulation, paclitaxel is bonded to albumin as a delivery vehicle. It is sometimes called nab-paclitaxel (with the "nab" syllable derived from "nanoparticle albumin–bound"). It is sold in the United States under the trade name Abraxane.This treatment was approved by the U.S.".
- Protein-bound_paclitaxel label "Protein-bound paclitaxel".
- Protein-bound_paclitaxel label "إيه بي آي-007".
- Protein-bound_paclitaxel sameAs Paclitaxel_lié_à_l'albumine.
- Protein-bound_paclitaxel sameAs m.02w4kys.
- Protein-bound_paclitaxel sameAs Q7251413.
- Protein-bound_paclitaxel sameAs Q7251413.
- Protein-bound_paclitaxel sameAs Protein-bound_paclitaxel.
- Protein-bound_paclitaxel wasDerivedFrom Protein-bound_paclitaxel?oldid=588860725.
- Protein-bound_paclitaxel isPrimaryTopicOf Protein-bound_paclitaxel.