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- RsmZ_RNA_family abstract "The PrrB/RsmZ RNA family are a group of related non-coding RNA molecules found in bacteria. PrrB RNA is able to phenotypically complement gacS and gacA mutants and is itself regulated by the GacS-GacA two-component signal transduction system. Inactivation of the prrB gene in Pseudomonas fluorescens F113 resulted in a significant reduction of 2, 4-diacetylphloroglucinol (Phl) and hydrogen cyanide (HCN) production, while increased metabolite production was observed when prrB was overexpressed. The prrB gene sequence contains a number of imperfect repeats of the consensus sequence 5'-AGGA-3', and sequence analysis predicted a complex secondary structure featuring multiple putative stem-loops with the consensus sequences predominantly positioned at the single-stranded regions at the ends of the stem-loops. This structure is similar to the CsrB and RsmB regulatory RNAs (CsrB/RsmB RNA family), suggesting this RNA also interacts with a CsrA-like protein.Studies in Legionella pneumophila have shown that the ncRNAs RsmY and RsmZ together with the proteins LetA and CsrA are involved in a regulatory cascade. Also, it appears that these ncRNAs are regulated by RpoS sigma-factor.".
- RsmZ_RNA_family thumbnail RF00166.jpg?width=300.
- RsmZ_RNA_family wikiPageExternalLink PF02599.
- RsmZ_RNA_family wikiPageID "11421018".
- RsmZ_RNA_family wikiPageRevisionID "592866943".
- RsmZ_RNA_family caption "Predicted secondary structure and sequence conservation of PrrB_RsmZ".
- RsmZ_RNA_family hasPhotoCollection RsmZ_RNA_family.
- RsmZ_RNA_family id "RF00166".
- RsmZ_RNA_family name "PrrB/RsmZ RNA family".
- RsmZ_RNA_family rfam "RF00166".
- RsmZ_RNA_family rnaType Bacterial_small_RNA.
- RsmZ_RNA_family rnaType Gene.
- RsmZ_RNA_family symbol "PrrB_RsmZ".
- RsmZ_RNA_family taxDomain Bacteria.
- RsmZ_RNA_family subject Category:Non-coding_RNA.
- RsmZ_RNA_family comment "The PrrB/RsmZ RNA family are a group of related non-coding RNA molecules found in bacteria. PrrB RNA is able to phenotypically complement gacS and gacA mutants and is itself regulated by the GacS-GacA two-component signal transduction system. Inactivation of the prrB gene in Pseudomonas fluorescens F113 resulted in a significant reduction of 2, 4-diacetylphloroglucinol (Phl) and hydrogen cyanide (HCN) production, while increased metabolite production was observed when prrB was overexpressed.".
- RsmZ_RNA_family label "PrrB/RsmZ RNA family".
- RsmZ_RNA_family sameAs m.02rbyn0.
- RsmZ_RNA_family sameAs Q7252933.
- RsmZ_RNA_family sameAs Q7252933.
- RsmZ_RNA_family wasDerivedFrom RsmZ_RNA_family?oldid=592866943.
- RsmZ_RNA_family depiction RF00166.jpg.
- RsmZ_RNA_family isPrimaryTopicOf RsmZ_RNA_family.
