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- Pseudophenmetrazine abstract "Pseudophenmetrazine is a psychostimulant compound of the morpholine class. It is the N-demethylated and cis-configured analogue of phendimetrazine as well as the cis-configured stereoisomer of phenmetrazine. In addition, along with phenmetrazine, it is believed to be one of the active metabolites of phendimetrazine, which itself is inactive and behaves merely as a prodrug. Relative to phenmetrazine, pseudophenmetrazine is of fairly low potency, acting as a modest releasing agent of norepinephrine (EC50 = 514 nM), while its (+)-enantiomer is a weak releaser of dopamine (EC50 = 1,457 nM) whereas its (-)-enantiomer is a weak reuptake inhibitor of dopamine (Ki = 2,691 nM); together as a racemic mixture with the two enantiomers combined, pseudophenmetrazine behaves overall more as a dopamine reuptake inhibitor (Ki = 2,630 nM), possibly due to the (+)-enantiomer blocking the uptake of the (-)-enantiomer into dopaminergic neurons and thus preventing it from inducing dopamine release. Neither enantiomer has any significant effect on serotonin reuptake or release (both Ki = >10,000 nM and EC50 = >10,000 nM, respectively).".
- Pseudophenmetrazine atcPrefix "None".
- Pseudophenmetrazine casNumber "13580-23-9".
- Pseudophenmetrazine iupacName "(±)-(2RS,3SR)-3-methyl-2-phenylmorpholine".
- Pseudophenmetrazine iupacName "(±)-cis-3-methyl-2-phenylmorpholine".
- Pseudophenmetrazine iupacName "or".
- Pseudophenmetrazine thumbnail Pseudophenmetrazine.svg?width=300.
- Pseudophenmetrazine wikiPageID "35866169".
- Pseudophenmetrazine wikiPageRevisionID "594402442".
- Pseudophenmetrazine atcPrefix "None".
- Pseudophenmetrazine c "11".
- Pseudophenmetrazine casNumber "13580".
- Pseudophenmetrazine h "15".
- Pseudophenmetrazine hasPhotoCollection Pseudophenmetrazine.
- Pseudophenmetrazine iupacName "--3-methyl-2-phenylmorpholine".
- Pseudophenmetrazine iupacName "-cis-3-methyl-2-phenylmorpholine".
- Pseudophenmetrazine iupacName "or".
- Pseudophenmetrazine molecularWeight "177.243".
- Pseudophenmetrazine n "1".
- Pseudophenmetrazine o "1".
- Pseudophenmetrazine subject Category:Dopamine_reuptake_inhibitors.
- Pseudophenmetrazine subject Category:Monoamine_releasing_agents.
- Pseudophenmetrazine subject Category:Morpholines.
- Pseudophenmetrazine subject Category:Stimulants.
- Pseudophenmetrazine type Drug.
- Pseudophenmetrazine type FunctionalSubstance.
- Pseudophenmetrazine comment "Pseudophenmetrazine is a psychostimulant compound of the morpholine class. It is the N-demethylated and cis-configured analogue of phendimetrazine as well as the cis-configured stereoisomer of phenmetrazine. In addition, along with phenmetrazine, it is believed to be one of the active metabolites of phendimetrazine, which itself is inactive and behaves merely as a prodrug.".
- Pseudophenmetrazine label "Pseudophenmetrazine".
- Pseudophenmetrazine sameAs m.0jwvn6y.
- Pseudophenmetrazine sameAs Q7255269.
- Pseudophenmetrazine sameAs Q7255269.
- Pseudophenmetrazine wasDerivedFrom Pseudophenmetrazine?oldid=594402442.
- Pseudophenmetrazine depiction Pseudophenmetrazine.svg.
- Pseudophenmetrazine isPrimaryTopicOf Pseudophenmetrazine.
