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- RASA3 abstract "Ras GTPase-activating protein 3 is an enzyme that in humans is encoded by the RASA3 gene.The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.".
- RASA3 entrezgene "22821".
- RASA3 wikiPageID "14879977".
- RASA3 wikiPageRevisionID "592903626".
- RASA3 hasPhotoCollection RASA3.
- RASA3 requireManualInspection "no".
- RASA3 summaryText "The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.".
- RASA3 updateCitations "yes".
- RASA3 updatePage "yes".
- RASA3 updateProteinBox "yes".
- RASA3 updateSummary "yes".
- RASA3 type Biomolecule.
- RASA3 type Protein.
- RASA3 type BiologicalObject.
- RASA3 comment "Ras GTPase-activating protein 3 is an enzyme that in humans is encoded by the RASA3 gene.The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart.".
- RASA3 label "RASA3".
- RASA3 sameAs m.03h0436.
- RASA3 sameAs Q7275817.
- RASA3 sameAs Q7275817.
- RASA3 wasDerivedFrom RASA3?oldid=592903626.
- RASA3 isPrimaryTopicOf RASA3.