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- RPL7 abstract "60S ribosomal protein L7' is a protein that in humans is encoded by the RPL7 gene.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.".
- RPL7 entrezgene "6129".
- RPL7 wikiPageID "14797471".
- RPL7 wikiPageRevisionID "592960157".
- RPL7 hasPhotoCollection RPL7.
- RPL7 requireManualInspection "no".
- RPL7 summaryText "Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper -like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.".
- RPL7 updateCitations "yes".
- RPL7 updatePage "yes".
- RPL7 updateProteinBox "yes".
- RPL7 updateSummary "yes".
- RPL7 type Biomolecule.
- RPL7 type Protein.
- RPL7 type BiologicalObject.
- RPL7 comment "60S ribosomal protein L7' is a protein that in humans is encoded by the RPL7 gene.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins.".
- RPL7 label "RPL7".
- RPL7 sameAs m.03gy8zj.
- RPL7 sameAs Q7277519.
- RPL7 sameAs Q7277519.
- RPL7 wasDerivedFrom RPL7?oldid=592960157.
- RPL7 isPrimaryTopicOf RPL7.