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- RTI-177 abstract "RTI-177 (2β-(3-phenylisoxazol-5-yl)-3β-(4-chlorophenyl)tropane, β-CPPIT) is a synthetic stimulant drug from the phenyltropane family, which acts as a DRI with micromolar affinity for the SERT. RTI-177 has an unusually long duration of action of 20 hours or more, substantially longer than the related compound RTI-336 from which it differs in molecular structure only by the absence of a p-methyl group."the nonselective monoamine transporter inhibitor RTI-126 and the DAT-selective inhibitors RTI-150 and RTI-336 both had a faster rate of onset (30 min) and a short duration of action (4h). In contrast, the nonselective monoamine transporter inhibitor RTI-112 had a slower rate of onset (30–60 min) and a longer duration of action (10h). The DAT-selective inhibitors RTI-171 and RTI-177 also had slower rates of onset (30–120 min), but RTI-171 had a short duration of action (2.5 h) while RTI-177 had a very long duration of action (20 h)."".
- RTI-177 iupacName "5-[(1R,2S,3S,]".
- RTI-177 pubchem "9800708".
- RTI-177 thumbnail RTI-onesevenseven.png?width=300.
- RTI-177 wikiPageExternalLink ?tool=pubmed.
- RTI-177 wikiPageID "23641979".
- RTI-177 wikiPageRevisionID "603893932".
- RTI-177 c "24".
- RTI-177 chembl "298580".
- RTI-177 cl "1".
- RTI-177 h "25".
- RTI-177 hasPhotoCollection RTI-177.
- RTI-177 iupacName "5".
- RTI-177 molecularWeight "392.92".
- RTI-177 n "2".
- RTI-177 o "1".
- RTI-177 pubchem "9800708".
- RTI-177 smiles "CC1=CC=CC2=NOC[C@@H]3[C@H]4CC[C@H]C[C@@H]3C5=CC=C".
- RTI-177 width "160".
- RTI-177 subject Category:Dopamine_reuptake_inhibitors.
- RTI-177 subject Category:Isoxazoles.
- RTI-177 subject Category:Organochlorides.
- RTI-177 subject Category:RTI_compounds.
- RTI-177 subject Category:Stimulants.
- RTI-177 subject Category:Tropanes.
- RTI-177 type Drug.
- RTI-177 type DrugProduct.
- RTI-177 type FunctionalSubstance.
- RTI-177 comment "RTI-177 (2β-(3-phenylisoxazol-5-yl)-3β-(4-chlorophenyl)tropane, β-CPPIT) is a synthetic stimulant drug from the phenyltropane family, which acts as a DRI with micromolar affinity for the SERT.".
- RTI-177 label "RTI-177".
- RTI-177 sameAs m.06zrl02.
- RTI-177 sameAs Q7277831.
- RTI-177 sameAs Q7277831.
- RTI-177 wasDerivedFrom RTI-177?oldid=603893932.
- RTI-177 depiction RTI-onesevenseven.png.
- RTI-177 isPrimaryTopicOf RTI-177.
