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- Randomized_controlled_trial abstract "A randomized controlled trial (or randomized control trial; RCT) is a specific type of scientific experiment, and the gold standard for a clinical trial. RCTs are often used to test the efficacy or effectiveness of various types of medical intervention within a patient population. RCTs may also provide an opportunity to gather useful information about adverse effects, such as drug reactions. The key distinguishing feature of the usual RCT is that study subjects, after assessment of eligibility and recruitment, but before the intervention to be studied begins, are randomly allocated to receive one or other of the alternative treatments under study. Random allocation in real trials is complex, but conceptually, the process is like tossing a coin. After randomization, the two (or more) groups of subjects are followed in exactly the same way, and the only differences between the care they receive, for example, in terms of procedures, tests, outpatient visits, and follow-up calls, should be those intrinsic to the treatments being compared. The most important advantage of proper randomization is that it minimizes allocation bias, balancing both known and unknown prognostic factors, in the assignment of treatments.The terms "RCT" and randomized trial are sometimes used synonymously, but the methodologically sound practice is to reserve the "RCT" name only for trials that contain control groups, in which groups receiving the experimental treatment are compared with control groups receiving no treatment (a placebo-controlled study) or a previously tested treatment (a positive-control study). The term "randomized trials" omits mention of controls and can describe studies that compare multiple treatment groups with each other (in the absence of a control group). Similarly, although the "RCT" name is sometimes expanded as "randomized clinical trial" or "randomized comparative trial", the methodologically sound practice, to avoid ambiguity in the scientific literature, is to retain "control" in the definition of "RCT" and thus reserve that name only for trials that contain controls. Not all randomized clinical trials are randomized controlled trials (and some of them could never be, in cases where controls would be impractical or unethical to institute). The term randomized controlled clinical trials is a methodologically sound alternate expansion for "RCT" in RCTs that concern clinical research; however, RCTs are also employed in other research areas, including many of the social sciences.".
- Randomized_controlled_trial thumbnail Flowchart_of_Phases_of_Parallel_Randomized_Trial_-_Modified_from_CONSORT_2010.png?width=300.
- Randomized_controlled_trial wikiPageExternalLink rctrials.org.
- Randomized_controlled_trial wikiPageExternalLink reflect-statement.org.
- Randomized_controlled_trial wikiPageExternalLink researghtool.org.
- Randomized_controlled_trial wikiPageExternalLink randsery.htm.
- Randomized_controlled_trial wikiPageExternalLink 8310.pdf.
- Randomized_controlled_trial wikiPageExternalLink www.icmje.org.
- Randomized_controlled_trial wikiPageExternalLink testing-treatments.pdf.
- Randomized_controlled_trial wikiPageExternalLink biostats-utmdabtr-002-06.pdf.
- Randomized_controlled_trial wikiPageID "163180".
- Randomized_controlled_trial wikiPageRevisionID "606024690".
- Randomized_controlled_trial hasPhotoCollection Randomized_controlled_trial.
- Randomized_controlled_trial subject Category:Causal_inference.
- Randomized_controlled_trial subject Category:Clinical_research.
- Randomized_controlled_trial subject Category:Design_of_experiments.
- Randomized_controlled_trial subject Category:Epidemiology.
- Randomized_controlled_trial subject Category:Evidence-based_practices.
- Randomized_controlled_trial subject Category:Experiments.
- Randomized_controlled_trial subject Category:Research_methods.
- Randomized_controlled_trial type Abstraction100002137.
- Randomized_controlled_trial type Act100030358.
- Randomized_controlled_trial type Activity100407535.
- Randomized_controlled_trial type Event100029378.
- Randomized_controlled_trial type Evidence-basedPractices.
- Randomized_controlled_trial type Practice100410247.
- Randomized_controlled_trial type PsychologicalFeature100023100.
- Randomized_controlled_trial type YagoPermanentlyLocatedEntity.
- Randomized_controlled_trial comment "A randomized controlled trial (or randomized control trial; RCT) is a specific type of scientific experiment, and the gold standard for a clinical trial. RCTs are often used to test the efficacy or effectiveness of various types of medical intervention within a patient population. RCTs may also provide an opportunity to gather useful information about adverse effects, such as drug reactions.".
- Randomized_controlled_trial label "Essai randomisé contrôlé".
- Randomized_controlled_trial label "Estudo clínico randomizado controlado".
- Randomized_controlled_trial label "Gerandomiseerd onderzoek met controlegroep".
- Randomized_controlled_trial label "Prueba controlada aleatoria".
- Randomized_controlled_trial label "Randomisierte kontrollierte Studie".
- Randomized_controlled_trial label "Randomized controlled trial".
- Randomized_controlled_trial label "ランダム化比較試験".
- Randomized_controlled_trial label "随机对照试验".
- Randomized_controlled_trial sameAs Randomisierte_kontrollierte_Studie.
- Randomized_controlled_trial sameAs Prueba_controlada_aleatoria.
- Randomized_controlled_trial sameAs Essai_randomisé_contrôlé.
- Randomized_controlled_trial sameAs Uji_acak_terkendali.
- Randomized_controlled_trial sameAs ランダム化比較試験.
- Randomized_controlled_trial sameAs Gerandomiseerd_onderzoek_met_controlegroep.
- Randomized_controlled_trial sameAs Estudo_clínico_randomizado_controlado.
- Randomized_controlled_trial sameAs m.015p9x.
- Randomized_controlled_trial sameAs Q1436668.
- Randomized_controlled_trial sameAs Q1436668.
- Randomized_controlled_trial sameAs Randomized_controlled_trial.
- Randomized_controlled_trial wasDerivedFrom Randomized_controlled_trial?oldid=606024690.
- Randomized_controlled_trial depiction Flowchart_of_Phases_of_Parallel_Randomized_Trial_-_Modified_from_CONSORT_2010.png.
- Randomized_controlled_trial isPrimaryTopicOf Randomized_controlled_trial.