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- Renal_cell_carcinoma abstract "Renal cell carcinoma (RCC, formerly known as hypernephroma, Grawitz tumor, renal adenocarcinoma) is a kidney cancer that originates in the lining of the proximal convoluted tubule, one type of very small tubes in the kidney that transports waste molecules from the blood to the urine. RCC is the most common type of kidney cancer in adults, responsible for approximately 90-95% of cases. It has been described as one of the deadliest of cancers affecting the genitourinary tract. Initial treatment is most commonly either partial or complete removal of the affected kidney(s) and remains the mainstay of curative treatment. Where the cancer has not metastasised (spread to other organs) or burrowed deeper into the tissues of the kidney the 5-year survival rate is 60-70%, but this is lowered considerably when the cancer has spread. It is relatively resistant to radiation therapy and chemotherapy, although some cases respond to targeted therapies such as sunitinib, temsirolimus, bevacizumab, interferon alfa and sorafenib have improved the outlook for RCC.The body is remarkably good at hiding the symptoms and as a result people with RCC often have advanced disease by the time it is discovered. The initial symptoms of RCC often include: blood in the urine (occurring in 40% of affected persons at the time they first seek medical attention), flank pain (40%), a mass in the abdomen or flank (25%), weight loss (33%), fever (20%), high blood pressure (20%), night sweats and generally feeling unwell. RCC is also associated with a number of paraneoplastic syndromes (PNS) which are conditions caused by either the hormones produced by the tumour or by the body's attack on the tumour and are present in about 20% of those with RCC. These syndromes most commonly affect tissues which have not been invaded by the cancer. The most common PNSs seen in people with RCC are: anaemia (due to an underproduction of the hormone, erythropoietin), high blood calcium levels, polycythaemia (the opposite to anaemia, due to an overproduction of erythropoietin), thrombocytosis (too many platelets in the blood, leading to an increased tendency for blood clots and bleeds) and secondary amyloidosis. When RCC metastasises it most commonly spreads to the lymph nodes, lungs, liver, adrenal glands, brain or bones.".
- Renal_cell_carcinoma diseasesdb "11245".
- Renal_cell_carcinoma emedicineSubject "med".
- Renal_cell_carcinoma emedicineTopic "2002".
- Renal_cell_carcinoma icd10 "C64".
- Renal_cell_carcinoma icd9 "189.0".
- Renal_cell_carcinoma medlineplus "000516".
- Renal_cell_carcinoma omim "144700".
- Renal_cell_carcinoma thumbnail Clear_cell_renal_cell_carcinoma_high_mag.jpg?width=300.
- Renal_cell_carcinoma wikiPageID "414178".
- Renal_cell_carcinoma wikiPageRevisionID "605500918".
- Renal_cell_carcinoma caption "Micrograph of the most common type of renal cell carcinoma - on right of the image; non-tumour kidney is on the left of the image. Nephrectomy specimen. H&E stain.".
- Renal_cell_carcinoma diseasesdb "11245".
- Renal_cell_carcinoma emedicinesubj "med".
- Renal_cell_carcinoma emedicinetopic "2002".
- Renal_cell_carcinoma hasPhotoCollection Renal_cell_carcinoma.
- Renal_cell_carcinoma icd "189".
- Renal_cell_carcinoma icd "64.0".
- Renal_cell_carcinoma medlineplus "516".
- Renal_cell_carcinoma meshi "D002292".
- Renal_cell_carcinoma name "Renal cell carcinoma".
- Renal_cell_carcinoma omim "144700".
- Renal_cell_carcinoma wordnet_type synset-disease-noun-1.
- Renal_cell_carcinoma subject Category:Kidney_cancer.
- Renal_cell_carcinoma type Abstraction100002137.
- Renal_cell_carcinoma type Attribute100024264.
- Renal_cell_carcinoma type Condition113920835.
- Renal_cell_carcinoma type Disease114070360.
- Renal_cell_carcinoma type IllHealth114052046.
- Renal_cell_carcinoma type Illness114061805.
- Renal_cell_carcinoma type PathologicalState114051917.
- Renal_cell_carcinoma type PhysicalCondition114034177.
- Renal_cell_carcinoma type State100024720.
- Renal_cell_carcinoma type Disease.
- Renal_cell_carcinoma type AilmentCondition.
- Renal_cell_carcinoma type Situation.
- Renal_cell_carcinoma comment "Renal cell carcinoma (RCC, formerly known as hypernephroma, Grawitz tumor, renal adenocarcinoma) is a kidney cancer that originates in the lining of the proximal convoluted tubule, one type of very small tubes in the kidney that transports waste molecules from the blood to the urine. RCC is the most common type of kidney cancer in adults, responsible for approximately 90-95% of cases. It has been described as one of the deadliest of cancers affecting the genitourinary tract.".
- Renal_cell_carcinoma label "Cancer du rein".
- Renal_cell_carcinoma label "Carcinoma a cellule renali".
- Renal_cell_carcinoma label "Carcinoma de células renais".
- Renal_cell_carcinoma label "Carcinoma renal".
- Renal_cell_carcinoma label "Niercelkanker".
- Renal_cell_carcinoma label "Nierenkrebs".
- Renal_cell_carcinoma label "Rak nerki".
- Renal_cell_carcinoma label "Renal cell carcinoma".
- Renal_cell_carcinoma label "Рак почки".
- Renal_cell_carcinoma label "腎細胞癌".
- Renal_cell_carcinoma sameAs Rakovina_ledvin.
- Renal_cell_carcinoma sameAs Nierenkrebs.
- Renal_cell_carcinoma sameAs Carcinoma_renal.
- Renal_cell_carcinoma sameAs Cancer_du_rein.
- Renal_cell_carcinoma sameAs Hipernefroma.
- Renal_cell_carcinoma sameAs Carcinoma_a_cellule_renali.
- Renal_cell_carcinoma sameAs 腎細胞癌.
- Renal_cell_carcinoma sameAs Niercelkanker.
- Renal_cell_carcinoma sameAs Rak_nerki.
- Renal_cell_carcinoma sameAs Carcinoma_de_células_renais.
- Renal_cell_carcinoma sameAs m.025hh9.
- Renal_cell_carcinoma sameAs Q1164529.
- Renal_cell_carcinoma sameAs Q1164529.
- Renal_cell_carcinoma sameAs 986.
- Renal_cell_carcinoma sameAs C1378703.
- Renal_cell_carcinoma sameAs Renal_cell_carcinoma.
- Renal_cell_carcinoma wasDerivedFrom Renal_cell_carcinoma?oldid=605500918.
- Renal_cell_carcinoma depiction Clear_cell_renal_cell_carcinoma_high_mag.jpg.
- Renal_cell_carcinoma isPrimaryTopicOf Renal_cell_carcinoma.
- Renal_cell_carcinoma name "Renal cell carcinoma".