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- Repinotan abstract "Repinotan (BAYx3702) is a selective 5-HT1A receptor full agonist with high potency and efficacy. It has neuroprotective effects in animal studies, and was trialled in humans for reducing brain injury following head trauma. It was subsequently trialled up to phase II for treatment of stroke, but while side effects were mild and consisted mainly of nausea, repinotan failed to demonstrate sufficient efficacy to justify further clinical trials. However repinotan continues to be investigated for other applications, and was found to be effective at counteracting the respiratory depression produced by morphine, though with slight reduction in analgesic effects.".
- Repinotan casNumber "144980-29-0".
- Repinotan fdaUniiCode "05PB82Z52L".
- Repinotan iupacName "(R)-(-)-2-[4-[(chroman-2-ylmethyl)-amino]-butyl]-1,1-dioxo-benzo[d]isothiazolone".
- Repinotan pubchem "198757".
- Repinotan thumbnail Repinotan.png?width=300.
- Repinotan wikiPageID "26620105".
- Repinotan wikiPageRevisionID "592917006".
- Repinotan c "21".
- Repinotan casNumber "144980".
- Repinotan chembl "1614652".
- Repinotan h "24".
- Repinotan hasPhotoCollection Repinotan.
- Repinotan iupacName "--2-[4-[-amino]-butyl]-1,1-dioxo-benzo[d]isothiazolone".
- Repinotan legalStatus "Uncontrolled".
- Repinotan molecularWeight "400.491".
- Repinotan n "2".
- Repinotan o "4".
- Repinotan pubchem "198757".
- Repinotan routesOfAdministration "Oral".
- Repinotan s "1".
- Repinotan smiles "C1CC2=CC=CC=C2O[C@H]1CNCCCCN3CC4=CC=CC=C4S3=O".
- Repinotan unii "5".
- Repinotan verifiedfields "changed".
- Repinotan verifiedrevid "381409135".
- Repinotan subject Category:Amines.
- Repinotan subject Category:Benzoisothiazolinones.
- Repinotan subject Category:Carboxamides.
- Repinotan subject Category:Chromanes.
- Repinotan type Abstraction100002137.
- Repinotan type AliphaticCompound114601294.
- Repinotan type Amine114739004.
- Repinotan type Amines.
- Repinotan type Chemical114806838.
- Repinotan type Compound114818238.
- Repinotan type Material114580897.
- Repinotan type Matter100020827.
- Repinotan type MethaneSeries114951377.
- Repinotan type OrganicCompound114727670.
- Repinotan type Part113809207.
- Repinotan type PhysicalEntity100001930.
- Repinotan type Relation100031921.
- Repinotan type Substance100019613.
- Repinotan type Drug.
- Repinotan type FunctionalSubstance.
- Repinotan comment "Repinotan (BAYx3702) is a selective 5-HT1A receptor full agonist with high potency and efficacy. It has neuroprotective effects in animal studies, and was trialled in humans for reducing brain injury following head trauma. It was subsequently trialled up to phase II for treatment of stroke, but while side effects were mild and consisted mainly of nausea, repinotan failed to demonstrate sufficient efficacy to justify further clinical trials.".
- Repinotan label "Repinotan".
- Repinotan sameAs m.0bh8fs7.
- Repinotan sameAs Q7314015.
- Repinotan sameAs Q7314015.
- Repinotan sameAs Repinotan.
- Repinotan wasDerivedFrom Repinotan?oldid=592917006.
- Repinotan depiction Repinotan.png.
- Repinotan isPrimaryTopicOf Repinotan.
