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- Replication_factor_C abstract "The replication factor C, or RFC, is a five-subunit protein complex that is required for DNA replication.The subunits of this heteropentamer are named Rfc1, Rfc2, Rfc3, Rfc4, and Rfc5 (in S. cerevisiae). RFC is used in eukaryotic replication as a clamp loader, similar to the γ Complex in E. coli. Its role as clamp loader involves catalysing the loading of PCNA on to DNA. It binds to the 3' end of the DNA and uses ATP to open the ring of PCNA so that it can encircle the DNA. ATP hydrolysis causes release of RFC, with concomitant clamp loading onto DNA.".
- Replication_factor_C wikiPageID "3875704".
- Replication_factor_C wikiPageRevisionID "546550140".
- Replication_factor_C hasPhotoCollection Replication_factor_C.
- Replication_factor_C subject Category:DNA_replication.
- Replication_factor_C comment "The replication factor C, or RFC, is a five-subunit protein complex that is required for DNA replication.The subunits of this heteropentamer are named Rfc1, Rfc2, Rfc3, Rfc4, and Rfc5 (in S. cerevisiae). RFC is used in eukaryotic replication as a clamp loader, similar to the γ Complex in E. coli. Its role as clamp loader involves catalysing the loading of PCNA on to DNA. It binds to the 3' end of the DNA and uses ATP to open the ring of PCNA so that it can encircle the DNA.".
- Replication_factor_C label "Replication factor C".
- Replication_factor_C sameAs m.0b4jyn.
- Replication_factor_C sameAs Q7314073.
- Replication_factor_C sameAs Q7314073.
- Replication_factor_C wasDerivedFrom Replication_factor_C?oldid=546550140.
- Replication_factor_C isPrimaryTopicOf Replication_factor_C.