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- Respiratory_burst abstract "Respiratory burst (sometimes called oxidative burst) is the rapid release of reactive oxygen species (superoxide radical and hydrogen peroxide) from different types of cells.Usually it denotes the release of these chemicals from immune cells, e.g., neutrophils and monocytes, as they come into contact with different bacteria or fungi. They are also released from the ovum of higher animals after the ovum has been fertilized. These substances can also be released from plant cells.Respiratory burst plays an important role in the immune system. It is a crucial reaction that occurs in phagocytes to degrade internalized particles and bacteria.NADPH oxidase, an enzyme family in the vasculature (in particular, in vascular disease), produces superoxide, which spontaneously recombines with other molecules to produce reactive free radicals. The superoxide reacts with NO, resulting in the formation of peroxynitrite, reducing the bioactive NO needed to dilate terminal arterioles and feed arteries and resistance arteries. Superoxide anion, peroxynitrite, and other reactive oxygen species also lead to pathology via peroxidation of proteins and lipids, and via activation of redox-sensitive signaling cascades and protein nitrosylation. NADPH oxidase activation has been suggested to depend on prior PKC activation. Myeloperoxidase uses the reactive oxygen species hydrogen peroxide to produce hypochlorous acid. Many vascular stimuli, including all those known to lead to insulin resistance, activate NADPH oxidase via both increased gene expression and complex activation mechanisms.To combat infections, immune cells use NADPH oxidase to reduce O2 to oxygen free radical and then H2O2. Neutrophils and monocytes utilize myeloperoxidase to further combine H2O2 with Cl- to produce hypochlorite, which plays a role in destroying bacteria. Absence of NADPH oxidase will prevent the formation of reactive oxygen species and will result in chronic granulomatous disease.".
- Respiratory_burst wikiPageID "1647815".
- Respiratory_burst wikiPageRevisionID "568948885".
- Respiratory_burst hasPhotoCollection Respiratory_burst.
- Respiratory_burst subject Category:Immune_system.
- Respiratory_burst subject Category:Leukocytes.
- Respiratory_burst type BloodCell105449268.
- Respiratory_burst type Cell100006484.
- Respiratory_burst type FreePhagocyte105451265.
- Respiratory_burst type Leukocyte105449959.
- Respiratory_burst type Leukocytes.
- Respiratory_burst type LivingThing100004258.
- Respiratory_burst type Object100002684.
- Respiratory_burst type Phagocyte105450888.
- Respiratory_burst type PhysicalEntity100001930.
- Respiratory_burst type SomaticCell105430628.
- Respiratory_burst type Whole100003553.
- Respiratory_burst comment "Respiratory burst (sometimes called oxidative burst) is the rapid release of reactive oxygen species (superoxide radical and hydrogen peroxide) from different types of cells.Usually it denotes the release of these chemicals from immune cells, e.g., neutrophils and monocytes, as they come into contact with different bacteria or fungi. They are also released from the ovum of higher animals after the ovum has been fertilized.".
- Respiratory_burst label "Estallido respiratorio".
- Respiratory_burst label "Oxidativer Burst".
- Respiratory_burst label "Respiratory burst".
- Respiratory_burst label "Wybuch tlenowy".
- Respiratory_burst sameAs Oxidativer_Burst.
- Respiratory_burst sameAs Estallido_respiratorio.
- Respiratory_burst sameAs 호흡폭발.
- Respiratory_burst sameAs Wybuch_tlenowy.
- Respiratory_burst sameAs m.05kfbq.
- Respiratory_burst sameAs Q838181.
- Respiratory_burst sameAs Q838181.
- Respiratory_burst sameAs Respiratory_burst.
- Respiratory_burst wasDerivedFrom Respiratory_burst?oldid=568948885.
- Respiratory_burst isPrimaryTopicOf Respiratory_burst.